Rs1131882 | CC | TT | TT | TT | CT | TT | TT, CT | TT, CT |
Rs1371097 | CC | TT | CT, TT | CT | CT | TT | TT | TT, CT |
Rs2317676 | AA | GG | GG | AG | AG | AG, GG | GG | GG, AG |
OR | 1 a | 2.76 | 1.99 | 2.11 | 1.06 | 1.14 | 1.17 | 1.05 |
95% CI | – | 1.27–7.89 | 1.03–5.12 | 1.08–6.15 | 0.87–1.77 | 0.88–2.23 | 0.94–2.87 | 0.81–1.92 |
P value | – | 0.002†| 0.023†| 0.018†| 0.213‡ | 0.385‡ | 0.165‡ | 0.467‡ |
- aThe wild type genotype for each genetic factor was used as the reference OR. OR, odds ratio; CI, confidence intervals
- †high-risk interactive genotypes were defined as there were significant associations between different combination of genotypes and carotid stenosis after adjustment with confounding variables (P < 0.05)
- ‡ low-risk interactive genotypes were defined as there were no significant associations between different combination of genotypes and carotid stenosis after adjustment with confounding variables (P > 0.05)