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Table 1 Summary of literatures results of MCS for refractory Pain

From: Motor cortex stimulation: a systematic literature-based analysis of effectiveness and case series experience

Literatures Center Etiology Duration
(months)
Follow-up
(months)
Analgesic effect
(VAS)
Improvement
Zhang 2017 [1] Xuanwu Hospital, China 16 Stroke 30.9 ± 28.3 28.2 ± 10.7 8.0 ± 0.7 - > 5.3 ± 2.4 33.67%
Rasche 2016 [2] University Hospital of Schleswig-Holstein, Germany 36 TNP NA 91.6 ± 33.6 9.2 ± 0.8 - > 5.0 ± 1.2 45.67%
Sokal 2015 [5] Military Research Hospital, Poland 6 Stroke; 2 TNP; 3 PA; 1 Phantom pain; 1 MS; 1 Syringomyelia 126.0 ± 82.7 39.4 ± 20.2 8.6 ± 0.6 - > 5.1 ± 2.3 41.03%
Slotty 2015 [6] Vancouver General Hospital, Canada 11 Stroke; 2 TNP; 4 PA; 4 SCI; 2 CRPS 64.9 ± 45.0 39.2 ± 19.6 7.7 ± 1.3 - > 6.9 ± 2.0 10.58%
Sachs 2014 [17] The Ottawa Hospital, Canada 1 Stroke; 7 TNP; 3 Phantom pain; 1 Facial hemangiopericytoma; 2 Vascular malformations NA 12.2 ± 12.4 7.2 ± 1.3 - > 5.7 ± 1.9 18.62%
Delavallee 2014 [19] Cliniques Universitaires Saint-Luc, Belgium 3 Stroke; 7 TNP; 3 PA; 1 Phantom pain; 3 Trauma; 1 CRPS 153.0 ± 138.6 103.1 ± 44.6 8.8 ± 0.7 - > 1.6 ± 1.2 81.70%
Buchanan 2014 [20] University Medical Center at Brackenridge, USA 2 Stroke; 5 TNP; 1 Phantom pain 24 36 9.5 ± 0.8 - > 5.5 ± 2.4 41.28%
Velasco 2008 [21] Mexico General Hospital, Mexico 1 Stroke; 3 PA; 5 Post-herpetic neuralgia; 1 Hemangiectasia syndrome; 1 Scleroderma 79.8 ± 63.6 12 9.5 ± 0.8 - > 3.6 ± 1.5 70.00%
Delavallee 2008 [11] Cliniques Universitaires Saint-Luc, Belgium 3 Stroke; 3 TNP; 1 PA; 1 Trauma 177 ± 160.5 NA 8.6 ± 0.5 - > 3.0 ± 2.6 65.63%
Rasche 2006 [22] University Hospital Heidelberg, Germany 7 Stroke; 9 TNP; 6 Surgical injury 66.7 ± 36.9 120 8.6 ± 0.9 - > 6.7 ± 2.5 23.45%
Pirotte 2005 [23] Universite Libre de Bruxelles, Belgium 6 Stroke; 4 TNP; 1 PA; 2 Spinal syrinx; 1 MS; 2 Amputation; 1 Surgical injury; 1 Post-radicular plexopathy NA 29.8 ± 16.9 7.5 ± 0.6 - > 3.7 ± 3.1 50.56%
Brown 2005 [24] Wayne State University School of Medicine, USA 2 Stroke; 4 TNP; 2 Post-herpetic neuralgia NA NA 9.0 ± 1.9 - > 3.9 ± 2.9 58.93%
  1. CRPS complex regional pain syndrome, TNP trigeminal neuropathic pain, PA plexus avulsion, SCI spinal cord injuries, MS multiple sclerosis, NA not available, VAS visual analogue scale, The data are recorded as mean ± Standard Deviation (SD)