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Table 1 Summary of literatures results of MCS for refractory Pain

From: Motor cortex stimulation: a systematic literature-based analysis of effectiveness and case series experience

Literatures

Center

Etiology

Duration

(months)

Follow-up

(months)

Analgesic effect

(VAS)

Improvement

Zhang 2017 [1]

Xuanwu Hospital, China

16 Stroke

30.9 ± 28.3

28.2 ± 10.7

8.0 ± 0.7 - > 5.3 ± 2.4

33.67%

Rasche 2016 [2]

University Hospital of Schleswig-Holstein, Germany

36 TNP

NA

91.6 ± 33.6

9.2 ± 0.8 - > 5.0 ± 1.2

45.67%

Sokal 2015 [5]

Military Research Hospital, Poland

6 Stroke; 2 TNP; 3 PA; 1 Phantom pain; 1 MS; 1 Syringomyelia

126.0 ± 82.7

39.4 ± 20.2

8.6 ± 0.6 - > 5.1 ± 2.3

41.03%

Slotty 2015 [6]

Vancouver General Hospital, Canada

11 Stroke; 2 TNP; 4 PA; 4 SCI; 2 CRPS

64.9 ± 45.0

39.2 ± 19.6

7.7 ± 1.3 - > 6.9 ± 2.0

10.58%

Sachs 2014 [17]

The Ottawa Hospital, Canada

1 Stroke; 7 TNP; 3 Phantom pain; 1 Facial hemangiopericytoma; 2 Vascular malformations

NA

12.2 ± 12.4

7.2 ± 1.3 - > 5.7 ± 1.9

18.62%

Delavallee 2014 [19]

Cliniques Universitaires Saint-Luc, Belgium

3 Stroke; 7 TNP; 3 PA; 1 Phantom pain; 3 Trauma; 1 CRPS

153.0 ± 138.6

103.1 ± 44.6

8.8 ± 0.7 - > 1.6 ± 1.2

81.70%

Buchanan 2014 [20]

University Medical Center at Brackenridge, USA

2 Stroke; 5 TNP; 1 Phantom pain

24

36

9.5 ± 0.8 - > 5.5 ± 2.4

41.28%

Velasco 2008 [21]

Mexico General Hospital, Mexico

1 Stroke; 3 PA; 5 Post-herpetic neuralgia; 1 Hemangiectasia syndrome; 1 Scleroderma

79.8 ± 63.6

12

9.5 ± 0.8 - > 3.6 ± 1.5

70.00%

Delavallee 2008 [11]

Cliniques Universitaires Saint-Luc, Belgium

3 Stroke; 3 TNP; 1 PA; 1 Trauma

177 ± 160.5

NA

8.6 ± 0.5 - > 3.0 ± 2.6

65.63%

Rasche 2006 [22]

University Hospital Heidelberg, Germany

7 Stroke; 9 TNP; 6 Surgical injury

66.7 ± 36.9

120

8.6 ± 0.9 - > 6.7 ± 2.5

23.45%

Pirotte 2005 [23]

Universite Libre de Bruxelles, Belgium

6 Stroke; 4 TNP; 1 PA; 2 Spinal syrinx; 1 MS; 2 Amputation; 1 Surgical injury; 1 Post-radicular plexopathy

NA

29.8 ± 16.9

7.5 ± 0.6 - > 3.7 ± 3.1

50.56%

Brown 2005 [24]

Wayne State University School of Medicine, USA

2 Stroke; 4 TNP; 2 Post-herpetic neuralgia

NA

NA

9.0 ± 1.9 - > 3.9 ± 2.9

58.93%

  1. CRPS complex regional pain syndrome, TNP trigeminal neuropathic pain, PA plexus avulsion, SCI spinal cord injuries, MS multiple sclerosis, NA not available, VAS visual analogue scale, The data are recorded as mean ± Standard Deviation (SD)