Fig. 2
From: Primary brain amyloidoma, both a neoplastic and a neurodegenerative disease: a case report
Histopathological and immunohistochemical characteristics of the cerebral amyloidoma. Large concentric sheets of Congo Red stained amyloid around an arteriole displaying the characteristic apple-green birefringence under polarized light and leading to an extraordinary thickening of the vessel wall (a), (original magnification × 25). Demonstration of the marked perivascular inflammatory reaction by visualizing macrophages (b) (CD68 immunostaining, original magnification × 200), T-lymphocytes (c), (CD3 immunostaining, original magnification × 100) and B-lymphocytes (d), (CD20 immunostaining, original magnification × 100). Hemosiderin-loaden macrophages indicating previous intraparenchymal microhemorrhage were encountered only very sporadically (arrows in e), (Prussian blue staining, original magnification × 50)