Table 1 Delphi criteria for APD [10]
From: Characterizing advanced Parkinson’s disease: OBSERVE-PD observational study results of 2615 patients
Delphi consensus criteria questions | Patient has |
|---|---|
1. Troublesome motor fluctuations, severity level | Moderate or severe |
2. “Off” time, hours/waking day | ≥ 2 or < 2 |
3. Nighttime sleep disturbances, severity level | Moderate or severe |
4. Troublesome dyskinesia, hours/waking day | 2–3 or > 3 |
5. Non-motor fluctuations present | Yes |
6. “Off” time at least every 3 h | Yes |
7. ≥ 5 times daily oral levodopa dosing | Yes |
8. Activities of daily living limitation, severity level | Moderate or severe |
9. Falling, frequency | Most of the time or all the time |
10. Dementia, severity level | Moderate or severe |
11. Psychosis, severity level | Moderate or Severe |