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Fig. 1 | BMC Neurology

Fig. 1

From: Monitoring treatment of Taenia solium- neurocysticercosis by detection of circulating antigens: a case report

Fig. 1

Timeline of the patient: Event flow and treatment monitoring and Antigen detecting enzyme linked immunosorbent assay (Ag-ELISA) assessment. Considering the day of infection as day 0, the first proglottids were observed in the stools on day 83. Tissue invasion probably occurred between day 83 and 90. A single dose praziquantel was given on day 90. Treatment for neurocysticercosis was given from day 172 till day 180. The Ag-ELISA results remained negative until day 135 when a slightly positive ratio of 1.2 was noted. This ratio gradually increased (i.e. 3.3 at day 142; 4.8 at day 149; 6.1 at day 158 and at day 178). On day 185 (i.e. five days after the end of treatment) there was a sharp decrease in circulating antigen (1.75). Since day 192 to year 2018 the test remained negative, i.e. no ratios higher than 1 were observed. Additionally, two MRI images were conducted in 2002 and 2008 without any evidence of lesions. Red line: Circulating antigen of Taenia solium metacestodes detected by Ag-ELISA, before and after anthelmintic treatment. Ratio = OD sample/OD cut-off (OD = Optical Density). Positivity starts at ratio-values above 1

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