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Table 2 Univariate and multivariate Fine-Gray models for the event emergence from altered consciousness state

From: Outcome prediction in disorders of consciousness: the role of coma recovery scale revised

 

Univariate

Multivariate †

HR (95% CI)

C Index

HR (95% CI)

C Index

Age (years)

1.01 (0.99–1.03)

0.313

1.00 (0.98–1.02)

 

Male (vs female)

0.76 (0.41–1.42)

0.585

0.71 (0.36–1.38)

 

MCS (vs VS)

9.36 (4.45–19.69)*

0.613

9.68 (4.46–21.01)*

0.708

CRS

1.36 (1.25–1.48)*

0.668

1.38 (1.26–1.52)*

0.699

Aetiology

 

0.554

  

 Anoxic (vs. Traumatic)

- §

 

–

 

 Vascular (vs. Traumatic)

1.25 (0.66–2.38)

 

1.00 (0.46–2.18)

 

IRU days

 

0.588

  

 31–59 (vs < 31)

0.82 (0.43–1.56)

 

0.56 (0.28–1.17)

 

 60–89 (vs < 31)

0.43 (0.15–1.27)

 

0.36 (0.12–1.11)

 

Tree Subgroups

 

0.604

  

 Subgroup B (vs A)

6.27 (0.61–842.86)

   

 Subgroup C (vs A)

10.33 (1.22–1346.99)*

   

 Subgroup D (vs A)

33.67 (4.57–4294.73)*

   

 Subgroup E (vs A)

81.77 (11.01–10,442.44)*

   
  1. † Both multivariate models have been developed with covariates Age, Sex, Aetiology, ICU days and, alternatively, MCS/VS state or CRS value at admission
  2. *: p < 0.05; § p < 0.05 for the k-sample test comparing the subdistribution for the event emergence
  3. HR: Hazard-Ratio; IRU: Intensive Rehabilitation Unit; MCS: minimally consciousness state; VS: Vegetative State; CRS: Coma-Recovery Scale
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BMC Neurology

ISSN: 1471-2377

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