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Table 3 Neurologic deterioration during hospitalization and outcome

From: Predictive factors of neurologic deterioration in patients with spontaneous cerebellar hemorrhage: a retrospective analysis

 

No neurologic deteriorated

N = 128

Neurologic deteriorated

N = 27

OR

P-Value

(1) Age (y), Median (range)

66.5 (18–87)

63 (20–86)

 

.288

(2) Male

70

14

1.099

.834

(3) Underlying diseases

 Hypertension

105

17

2.175

.038

 Diabetes mellitus

37

7

1.133

.819

 End-stage renal failure

6

4

.397

.073

 Liver cirrhosis

5

4

.354

.050

 Atrial fibrillation

8

2

.862

.686

 Coronary artery disease

5

0

.820

.588

 Valvular heart disease

8

3

.615

.409

 Old cerebral vascular accidents

22

4

.806

.568

 Alcoholism

12

4

.662

.483

 Smoking

13

6

.489

.104

(4) Clinical feature at presentation

    

 Headache

46

14

.586

.134

 Nausea, vomiting

77

13

1.491

.287

 Unsteady gait

19

1

3.852

.202

 Loss of consciousness

29

12

.450

.029

 Limbs weakness

5

0

.820

.588

 Pupil had light reflex

111

19

1.955

.240

(5) Laboratory data at presentation, Median (IQR)

 Heart rate, per minutes

81 (70, 95)

89 (84, 107)

 

.010

 Systolic blood pressure, mmHg

164 (142, 193)

170 (143, 219)

 

.439

 Diastolic blood pressure, mmHg

88 (77, 101)

90 (69, 101)

 

.839

 WBC (X103/mL)

9.6 (7.2, 13.1)

11 (7.9, 13.8)

 

.237

 Platelet counts (X103/mL)

197 (152, 230)

146 (81, 233)

 

.070

 Partial thromboplastin time, seconds

10.3 (10.0, 11.0)

10.7 (9.8, 12.7)

 

.581

 International normalized ratio

1.0 (0.95, 1.07)

1.02 (0.91, 1.24)

 

.978

 Blood sugar, mmol/L

153 (128, 197)

151 (133, 246)

 

.655

(6) Brain Imagies Findings at presentation

 CH volume (mm3)

5.8 (1.9, 12.2)

20.2 (11.5, 35.1)

 

.000

 Obliteration of basal cistern

60

24

.154

.000

 Intraventricular hemorrhage

99

25

.331

.108

 Hydrocephalus

48

21

.235

.000

(7) Median (IQR) GCS at presentation

15 (12, 15)

7 (5, 14)

 

.000

(8) Surgical intervention

 Extraventricular drainage (EVD)

4

2 (2a)

  

 Suboccipital craniectomy

6

6 (1a)

  

 Suboccipital craniectomy + EVD

17

15 (6a)

  

 Ventriculo-Peritoneal Shunt

19

6

  

(9) ICH score, Median (IQR)

2 (2, 3)

3 (2, 4)

 

.000

(10) Outcome at discharged

 Good

113

1

.014

.000

 Mortality

4

22

.046

.000

  1. GCS Glasgow coma score, OR odds ratio, SD standard deviation, IQR interquartile range, ICU intensive care unit,
  2. CH cerebellar hemorrhage
  3. (a): emergent surgery while conscious deteriorated during hospitalization
  4. Numerical variables were analyzed by Mann—Whitney U-test and Categorical variables were analyzed by chi-squared test and Fisher’s exact test