Fig. 1

Clinical symptoms, MRI, CSF leukocytes and treatment since the onset of the disease. From the age of 7 years, a female patient had 10 disease recurrences, including 4 episodes of recurrent optic neuritis, 4 episodes of fever and meningoencephalitis, and 2 episodes of optic neuritis as well as meningoencephalitis. High dose intravenous methylprednisolone was the main treatment for relapses. Azathioprine, oral methylprednisolone and intermittent intravenous methylprednisolone were used in remission