Table 2 Change over Time in Outcomes by Treatment Group 1
P-values | |||||
|---|---|---|---|---|---|
Standard Care | In-person | mHealth | In-person vs SC | mHealth vs SC | |
Change in ALSFRS-R at month 3 | −1.9 (− 3.4, − 0.3) | −2.1 (− 3.8, − 0.5) | − 2.0 (− 3.8, − 0.3) | 0.80 | 0.88 |
Change in ALSFRS-R at month 6 | −5.2 (− 7.6, − 2.9) | −5.8 (− 8.2, − 3.4) | − 2.6 (− 5.1, − 0.1) | 0.74 | 0.13 |
Change in PROMIS QOL at month 3 | −2.1 (− 4.0, − 0.2) | − 1.0 (− 2.9, 0.8) | 0.3 (− 1.7, 2.2) | 0.42 | 0.08 |
Change in PROMIS QOL at month 6 | −2.8 (− 5.2, − 0.5) | −2.3 (− 4.6, − 0.1) | −1.9 (− 4.4, 0.5) | 0.77 | 0.59 |
Change in Weight at month 3 (kg) | −0.0 (−1.4, 1.3) | − 0.1 (− 1.5, 1.3) | 0.3 (− 1.1, 1.8) | 0.95 | 0.70 |
Change in Weight at month 6 (kg) | − 1.2 (− 3.2, 0.7) | − 0.1 (− 2.1, 2.0) | −0.2 (− 2.4, 2.1) | 0.41 | 0.47 |
Change in % Calories at month 3 | −0.6 (− 10.4, 9.2) | 6.8 (− 2.5, 16.0) | 12.2 (2.5, 21.8) | 0.26 | 0.06 |
Change in % Calories at month 6 | 3.5 (−7.9, 14.9) | 7.6 (−3.9, 19.2) | 1.0 (− 10.7, 12.6) | 0.59 | 0.75 |
Change in total kCal at month 3 | −35.3 (− 368.8, 298.1) | 250.3 (− 65.2, 565.8) | 308.2 (− 21.2, 637.6) | 0.21 | 0.14 |
Change in total kCal at month 6 | 83.9 (− 298.7, 466.4) | 78.2 (− 295.5, 451.8) | −33.7 (− 424.5, 357.1) | 0.98 | 0.66 |