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Table 2 Association of SNPs of candidate genes and odds ratio to ET risk (ET without RLS)

From: IL1B polymorphism is associated with essential tremor in Chinese population

Gene SNP HWE p value MAF (case/control) Allele
Minor allele OR 95%CI p
HMOX1 rs2071746 0.701 0.44/0.46 A 0.90 (0.69, 1.18) 0.452
HMOX2 rs4786504 0.031
rs1051308 0.983 0.37/0.37 G 1.00 (0.75, 1.32) 0.983
VDR rs731236 0.255 0.07/0.05 C 1.47 (0.81, 2.65) 0.203
IL17A rs8193036 0.735 0.30/0.30 T 1.04 (0.77, 1.39) 0.809
IL1B rs1143643 0.591 0.46/0.43 G 1.13 (0.86, 1.48) 0.389
rs1143634 0.431 0.04/0.02 T 1.64 (0.72, 3.75) 0.232
rs1143633 0.272 0.38/0.34 G 1.22 (0.92, 1.61) 0.171
NOS1 rs693534 0.910 0.27/0.27 A 1.03 (0.76, 1.40) 0.858
rs7977109 0.828 0.22/0.23 G 0.96 (0.69, 1.32) 0.781
ADH1B rs6413413
rs1229984 0.729 0.33/0.32 G 1.07 (0.80, 1.43) 0.644
Gene SNP Dominant Model (adjusted) Recessive Model (adjusted) Genetic Power
OR 95%CI p OR 95%CI p
HMOX1 rs2071746 0.86 (0.56, 1.32) 0.503 0.90 (0.55, 1.47) 0.671 0.084
HMOX2 rs4786504
rs1051308 0.93 (0.62, 1.37) 0.701 1.09 (0.61, 1.96) 0.762 0.050
VDR rs731236 1.51 (0.82, 2.80) 0.188 0.394
IL17A rs8193036 0.98 (0.66, 1.44) 0.909 1.22 (0.64, 2.34) 0.549 0.053
IL1B rs1143643 0.87 (0.57, 1.33) 0.516 1.86 (1.12, 3.11) 0.017 0.095
rs1143634 1.68 (0.71, 3.96) 0.234 0.629
rs1143633 1.01 (0.68, 1.50) 0.948 2.57 (1.38, 4.81) 0.003 0.127
NOS1 rs693534 0.96 (0.65, 1.41) 0.829 1.33 (0.63, 2.82) 0.455 0.051
rs7977109 0.98 (0.66, 1.46) 0.938 0.74 (0.29, 1.86) 0.519 0.054
ADH1B rs6413413
rs1229984 0.99 (0.67, 1.46) 0.946 1.58 (0.76, 3.25) 0.219 0.063