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Table 1 Baseline characteristics of the patients

From: Intravenous fibrinolysis plus endovascular thrombectomy versus direct endovascular thrombectomy for anterior circulation acute ischemic stroke: clinical and infarct volume results

Characteristics CoT (n = 70) Direct ET (n = 75) b
Age, Mean (SD), y 71.9 (10.6) 69.1 (13.2) 0.152
Gender, n F (%) 32 (45.7) 38 (50.6) 0.49a
Baseline NIHSS, median (IQR) 18 (15–21) 19 (15–20) 0.55c
Risk factors
 Hypertension, n (%) 52 (74.3) 53 (70.6) 0.62a
 Diabetes mellitus, n (%) 12 (17.1) 11 (14.6) 0.68a
 Atrial fibrillation, n (%) 30 (42.8) 37 (49.3) 0.43a
 Hyperlipidemia, n (%) 29 (41.4) 23 (30.6) 0.17a
Antiplatelet or anticoagulant use, n (%) 34 (48.6) 37 (49.3) 0.85a
Sistolic Blood Pressure, Mean (SD), mmHg 145.6 (12.6) 147.3 (24.8) 0.70b
Diastolic Blood Pressure, Mean (SD), mmHg 81.9 (15.3) 81.1 (12.5) 0.77b
Serum glucose, Mean (SD), mg/dl 130.4 (54.6) 139.4 (82.7) 0.59b
ASPECTS score; median (IQR) 9 (8–10) 9 (8–10) 0.06c
Cause of stroke (TOAST)    0.7
 Large-artery disease, (%) 23.4 20.0  
 Small-artery disease, (%) 0.0 0.0  
 Cardioembolic, (%) 54.7 55.0  
 Other, (%) 4.7 6.6  
Unknown, (%) 17.2 18.4  
Site of occlusion
 tICA, n (%) 9 (12.8) 22 (29.3) 0.06a
 MCA-M1 segment, n (%) 46 (65.7) 40 (53.3)  
 MCA-M2 segment, n (%) 15 (21.4) 13 (17.3)  
  1. aPearson’s chi-squared test; bMann-Whitney test for unpaired groups; cWilcoxon rank sum test; IQR inter-quartile range, NIHSS National Institute of Health Stroke Scalem, SD standard deviation, MCA middle cerebral artery, tICA terminal ICA, PCSE potential cardiac sources of embolism, CoT combined therapy, ET endovascular therapy