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Table 3 Details of procedural, clinical, and safety outcomes

From: Intravenous fibrinolysis plus endovascular thrombectomy versus direct endovascular thrombectomy for anterior circulation acute ischemic stroke: clinical and infarct volume results

Variables

CoT (n = 70)

Direct ET (n = 75)

P Value

Time from symptoms onset to needle, Mean (SD), min

156.1 (37.6)

n.a

n.a

Time from symptoms onset to groin puncture, Mean (SD), min

194.1 (59.9)

204.8 (60.4)

0.322

Time from symptoms onset to recanalization, Mean (SD), min

245.9 (75.8)

245.1 (58.6)

0.952

TICI 2b or 3 reperfusion, n (%)

59 (84.3)

49 (65.3)

0.0091

Rates of first-pass success, %

62.7

38.6

< 0.051

sICH, n (%)

7 (10.0)

8 (10.6)

0.871

Cerebral infarct Volume, Mean (SD), ml

16.4 (25.3)

62.3 (81.7)

0.0032

Outcome at 90 days

 mRS score of 0–1, n (%)

34 (48.5)

14 (18.6)

< 0.0011

 mRS score of 0–2, n (%)

47 (67.1)

28 (37.3)

< 0.0011

 Mortality, n (%)

5 (7.1)

11 (14.6)

0.151

  1. 1Pearson’s chi-squared test; 2 Mann-Whitney test for unpaired groups; CoT combined therapy, ET endovascular therapy, SD standard deviation, ICH intracerebral hemorrhage, mRS modified Rankin Scale, TICI thrombolysis in cerebral infarction grading scale