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Table 3 Details of procedural, clinical, and safety outcomes

From: Intravenous fibrinolysis plus endovascular thrombectomy versus direct endovascular thrombectomy for anterior circulation acute ischemic stroke: clinical and infarct volume results

Variables CoT (n = 70) Direct ET (n = 75) P Value
Time from symptoms onset to needle, Mean (SD), min 156.1 (37.6) n.a n.a
Time from symptoms onset to groin puncture, Mean (SD), min 194.1 (59.9) 204.8 (60.4) 0.322
Time from symptoms onset to recanalization, Mean (SD), min 245.9 (75.8) 245.1 (58.6) 0.952
TICI 2b or 3 reperfusion, n (%) 59 (84.3) 49 (65.3) 0.0091
Rates of first-pass success, % 62.7 38.6 < 0.051
sICH, n (%) 7 (10.0) 8 (10.6) 0.871
Cerebral infarct Volume, Mean (SD), ml 16.4 (25.3) 62.3 (81.7) 0.0032
Outcome at 90 days
 mRS score of 0–1, n (%) 34 (48.5) 14 (18.6) < 0.0011
 mRS score of 0–2, n (%) 47 (67.1) 28 (37.3) < 0.0011
 Mortality, n (%) 5 (7.1) 11 (14.6) 0.151
  1. 1Pearson’s chi-squared test; 2 Mann-Whitney test for unpaired groups; CoT combined therapy, ET endovascular therapy, SD standard deviation, ICH intracerebral hemorrhage, mRS modified Rankin Scale, TICI thrombolysis in cerebral infarction grading scale