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Table 1 Spearman correlation coefficients of each CSF protein level with patient background and motor symptoms

From: Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson’s disease

  Patient background Motor symptoms
   Age Education Duration from symptom onset UPDRS part III Tremor Rigidity Bradykinesia Gait Postural instability
Total αS r 0.362 0.216 −0.314 − 0.446* 0.192 − 0.331 − 0.528** − 0.245 −0.356
  p 0.0635 0.2794 0.1104 0.0289 0.3692 0.1136 0.0080 0.2482 0.0873
  n 27 27 27 24 24 24 24 24 24
O-αS r 0.010 −0.036 0.203 −0.205 0.265 − 0.119 −0.224 − 0.335 −0.310
  p 0.9614 0.8594 0.3105 0.3356 0.2101 0.5792 0.2928 0.1095 0.1407
  n 27 27 27 24 24 24 24 24 24
Aβ1–42 r 0.292 0.131 −0.231 −0.085 0.140 −0.024 −0.107 − 0.160 −0.047
  p 0.1389 0.5150 0.2473 0.6913 0.5141 0.9104 0.6203 0.4546 0.8283
  n 27 27 27 24 24 24 24 24 24
Total tau r 0.334 0.180 −0.212 −0.297 0.002 −0.195 −0.426* − 0.167 −0.163
  p 0.0886 0.3702 0.2877 0.1581 0.9934 0.3610 0.0379 0.4346 0.4457
  n 27 27 27 24 24 24 24 24 24
P-tau181p r 0.491* 0.081 −0.032 −0.448* 0.029 −0.425* −0.462* − 0.048 −0.338
  p 0.0126 0.7004 0.8804 0.0365 0.8978 0.0486 0.0303 0.8317 0.1241
  n 25 25 25 22 22 22 22 22 22
  1. *: p < 0.05, **: p < 0.01
  2. Abbreviations: Total αS, Total α-synuclein; O-αS, Oligomeric α-synuclein; P-tau181p, tau phosphorylated at threonine 181; UPDRS Unified Parkinson’s Disease Rating Scale