Table 4 Patient background

Male: Female

14:13

Age (years)

72.3 ± 9.2

(range 47–84)

Education (years)

12.2 ± 3.2

(range 3–16)

Duration from symptom onset (years)

1.3 ± 1.2

(<  1 year

7 persons)

(≥ 1, <  2 years

12 persons)

(≥ 2, <  3 years

4 persons)

(≥ 3, <  4 years

3 persons)

(≥ 4, <  5 years

0 person)

(≥ 5, <  6 years

1 person)

 Part III (motor score)

16.7 ± 8.2

(range 5–31)

 Tremor

2.6 ± 2.6

(range 0–10)

 Rigidity

3.0 ± 2.3

(range 0–10)

 Bradykinesia

6.4 ± 4.4

(range 0–16)

 Gait

2.5 ± 2.0

(range 0–7)

 Postural instability

2.4 ± 1.9

(range 0–6)

 MoCA

21.7 ± 5.5

(range 9–28)

 Orientation

8.9 ± 1.3

(range 6–10)

 Attention

6.3 ± 3.8

(range 1–10)

 Language-comprehension

8.7 ± 2.9

(range 1–10)

 Language-repetition

8.6 ± 2.3

(range 4–11)

 Language-naming

9.0 ± 1.6

(range 5–10)

Construction

7.5 ± 1.8

(range 4–11)

 Memory

7.5 ± 1.7

(range 5–10)

 Calculation

8.6 ± 2.5

(range 2–10)

 Similarity

9.1 ± 1.2

(range 6–11)

 Judgement

9.8 ± 1.3

(range 7–12)

 Total αS (pg/ml)

1517.3 ± 654.3

(range 573–3387)

 O-αS (RLU/s)

107,019.5 ± 20,203.1

(range 74,867–161,685)

 Aβ1–42 (pg/ml)

427.1 ± 159.7

(range 206.4–724.5)

 Total tau (pg/ml)

38.4 ± 21.2

(range 11.2–93.9)

 P-tau181p (pg/ml)

15.3 ± 6.1

(range 5.8–29.9)