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Table 2 Electrophysiological parameters in healthy controls, and in the group of migraine patients before and after 1-month KD

From: A ketogenic diet normalizes interictal cortical but not subcortical responsivity in migraineurs

 

HV

KD Before

KD After

ST

3.1 ± 4.6

2.5 ± 1.2

2.5 ± 1.5

PT

14.1 ± 5.6

10.5 ± 4.6

11.1 ± 5.6

VAS (0–10)

7.0 ± 2.1

7.1 ± 1.8

6.9 ± 1.2

Nociceptive Blink Reflex (nBR)

Homolateral R2 onset (ms)

32 ± 4.4

33.9 ± 7.9

32.9 ± 6.4

Homolateral R2 1st AUC block (μV x ms)

1.2 ± 0.6

0.5 ± 0.3 §

0.6 ± 0.3 §

Homolateral R2 slope

- 0.15 ± 0.11

0.02 ± 0.18 §

0.02 ± 0.17 §

Contralateral R2 onset (ms)

33.3 ± 4.6

33.7 ± 7.7

33.0 ± 5.9

Contralateral R2 1st AUC block (μV x ms)

1.1 ± 0.7

0.5 ± 0.4 §

0.5 ± 0.3 §

Contralateral R2 slope

- 0.17 ± 0.37

0.005 ± 0.17

0.02 ± 0.11

Pain-related evoked potentials (PREP)

N (ms)

124.4 ± 16.3

127.0 ± 12.0

131.8 ± 18.0

P (ms)

241.2 ± 59.1

218.3 ± 30.1

224.5 ± 26.8

N-P 1st amplitude block (μV)

50.9 ± 28.5

39.1 ± 18.1

46.1 ± 19.1

N-P amplitude slope

- 6.9 ± 8.0

2.9 ± 11.0 §

- 9.1 ± 15.5 *

  1. Data are expressed as means ± SD. * = p ≤ 0.01 before vs. after 1-month KD. § = p < 0.01 vs. HV