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Table 2 Baseline patient characteristics dichotomized according to blood eosinophil count

From: Absolute blood eosinophil count could be a potential biomarker for predicting haemorrhagic transformation after intravenous thrombolysis for acute ischaemic stroke

 

AEC < 0.11, × 109/l (86, 42.8%)

AEC ≥ 0.11, ×  109/l (115, 57.2%)

p value

Age, years

79.0 (70.25–84.25)

76.0 (70.0–83.0)

0.530

Sex, female

49 (57.0%)

71 (61.7%)

0.496

HT

16 (18.6%)

7 (6.1%)

0.006

sICH

9 (10.5%)

5 (4.3%)

0.092

Time to the start of IVT, min

160.0 (120.0–196.3)

145.0 (110.0–180.0)

0.048

Baseline NIHSS

9.0 (5.8–16.0)

10.0 (7.0–14.0)

0.416

SBP, mmHg

167.5 (±27.5)

164.7 (±29.6)

0.501

DBP, mmHg

94.7 (±16.4)

92.6 (±17.1)

0.390

INR

1.02 (0.97–1.10)

1.02 (0.95–1.07)

0.214

GFR, ml/min/1.73m2

61.23 (44.93–75.52)

62.83 (52.34–73.81)

0.594

Blood glucose, mmol/l

6.59 (5.81–7.72)

6.66 (6.02–7.73)

0.501

Haemoglobin, g/l

134.2 (±15.8)

134.2 (±15.6)

0.996

Neutrophils, × 109/l

4.52 (3.40–6.66)

4.55 (3.65–5.54)

0.434

Lymphocytes, × 109/l

1.61 (1.24–2.16)

2.21 (1.72–2.91)

< 0.001

Monocytes, × 109/l

0.58 (0.46–0.74)

0.68 (0.53–0.85)

0.003

NLR

2.84 (1.75–4.80)

1.91 (1.49–2.91)

0.001

LMR

2.76 (2.06–3.81)

3.20 (2.61–4.82)

< 0.001

Platelets, × 109/l

202.5 (171.0–244.3)

220.0 (183.0–262.0)

0.038

Diabetes mellitus

7 (8.1%)

28 (24.3%)

0.003

Atrial fibrillation at admission

34 (39.5%)

41 (35.7%)

0.573

Previous stroke

8 (9.3%)

16 (13.9%)

0.319

Pre-admission anticoagulant use

10 (11.6%)

9 (7.8%)

0.362

Pre-admission antiaggregant use

16 (18.6%)

20 (17.4%)

0.824

  1. Values are given as n (%), mean (SD), or median (IQR). AEC absolute eosinophil count, DBP diastolic blood pressure, GFR glomerular filtration rate, HT haemorrhagic transformation, INR international normalized ratio, IVT intravenous thrombolysis, LMR lymphocyte to monocyte ratio, NIHSS National Institutes of Health Stroke Scale, NLR neutrophil to lymphocyte ratio, SBP systolic blood pressure, sICH symptomatic intracranial haemorrhage