Table 1 Comparison of pathological findings between DM1, DM2 and the present case
Present case | DM1 | DM2 | NDMs | |
|---|---|---|---|---|
Fiber size variation | ++ | +++ | +++ | + |
Endomysial fibrosis | + | +++ | ++ | ± |
Increase of internal nuclei | +++ | +++ | +++ | ± |
Pyknotic nuclear clumps | + | + | +++ | – |
Sarcoplasmic masses | – | ++ | ± | – |
Chained nuclei | + | + | unknown | – |
Fiber splitting | + | + | unknown | – |
Ragged red fibers | – | + | ± | – |
Fiber type predominancy | 2A > 1> > 2B | type1 | type1 | 2A > 1> > 2B |
Type of atrophy | nonspecific | type1 > type2 | type2 | type2B |
Ring fibers | – | ++ | ± | – |
Fatty replacement | + | +++ | ++ | – |