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Table 1 Comparison of clinical profiles between controls and patients with severe extracranial carotid artery stenosis (CAS)

From: Metabolomics study in severe extracranial carotid artery stenosis

  Group
Control CAS p value
n = 65 n = 65
Age (years) 61.3 ± 5.2 63.2 ± 5.7 0.050
Male, n (%) 65 (100) 65 (100)  
Ischemic stroke, n (%) 0 (0) 63 (97.0) < 0.001
Coronary artery disease, n (%) 4 (6.2) 19 (29.2) < 0.001
Risk factor profile
 Hypertension, n (%) 25 (38.5) 48 (73.8) < 0.001
 Atrial fibrillation, n (%) 0 (0) 0 (0)  
 Smoking, n (%) 25 (38.5) 52 (80.0) < 0.001
 Alcohol, n (%) 14 (22.5) 26 (40.0) 0.039
 Hx of recurrent stroke, n (%) 0 (0) 18 (27.7) < 0.001
 Body mass index (kg/m2) 25.7 ± 7.0 24.6 ± 6.0 0.058
Laboratory blood test
 Homocysteine (mg/dL) 10.3 ± 4.0 12.9 ± 7.8 0.011
 HS-CRP (mg/dL) 2.5 ± 5.8 3.2 ± 3.3 0.446
 Total Cholesterol (mg/dL) 209.1 ± 43.2 178.9 ± 50.5 < 0.001
 Triglyceride (mg/dL) 146.5 ± 78.0 135.5 ± 77.6 0.418
 LDL-C (mg/dL) 123.2 ± 41.8 112.5 ± 38.8 0.105
 HDL-C (mg/dL) 48.0 ± 13.2 38.9 ± 10.9 < 0.001
 Serum sodium (mEq/L) 141.2 ± 47.0 140.3 ± 68.3 0.219
 Hemoglobin (g/dL) 14.7 ± 7.4 13.7 ± 5.9 0.018
 AC sugar (mg/dL) 100.7 ± 36.6 97.6 ± 49.4 0.304
 Uric acid (mg/dL) 6.6 ± 1.9 6.3 ± 2.3 0.358
 eGFR (ml/min/1.73 m2) 75.2 ± 28.1 84.0 ± 46.3 0.319
  1. Patients with diabetes are excluded from the study. LDL-C low density lipoprotein-cholesterol, HDL-C high density lipoprotein-cholesterol, eGFR estimated glomerular filtration rate