From: Metabolomics study in severe extracranial carotid artery stenosis
 | Group | ||
---|---|---|---|
Control | CAS | p value | |
n = 65 | n = 65 | ||
Age (years) | 61.3 ± 5.2 | 63.2 ± 5.7 | 0.050 |
Male, n (%) | 65 (100) | 65 (100) | Â |
Ischemic stroke, n (%) | 0 (0) | 63 (97.0) | < 0.001 |
Coronary artery disease, n (%) | 4 (6.2) | 19 (29.2) | < 0.001 |
Risk factor profile | |||
 Hypertension, n (%) | 25 (38.5) | 48 (73.8) | < 0.001 |
 Atrial fibrillation, n (%) | 0 (0) | 0 (0) |  |
 Smoking, n (%) | 25 (38.5) | 52 (80.0) | < 0.001 |
 Alcohol, n (%) | 14 (22.5) | 26 (40.0) | 0.039 |
 Hx of recurrent stroke, n (%) | 0 (0) | 18 (27.7) | < 0.001 |
 Body mass index (kg/m2) | 25.7 ± 7.0 | 24.6 ± 6.0 | 0.058 |
Laboratory blood test | |||
 Homocysteine (mg/dL) | 10.3 ± 4.0 | 12.9 ± 7.8 | 0.011 |
 HS-CRP (mg/dL) | 2.5 ± 5.8 | 3.2 ± 3.3 | 0.446 |
 Total Cholesterol (mg/dL) | 209.1 ± 43.2 | 178.9 ± 50.5 | < 0.001 |
 Triglyceride (mg/dL) | 146.5 ± 78.0 | 135.5 ± 77.6 | 0.418 |
 LDL-C (mg/dL) | 123.2 ± 41.8 | 112.5 ± 38.8 | 0.105 |
 HDL-C (mg/dL) | 48.0 ± 13.2 | 38.9 ± 10.9 | < 0.001 |
 Serum sodium (mEq/L) | 141.2 ± 47.0 | 140.3 ± 68.3 | 0.219 |
 Hemoglobin (g/dL) | 14.7 ± 7.4 | 13.7 ± 5.9 | 0.018 |
 AC sugar (mg/dL) | 100.7 ± 36.6 | 97.6 ± 49.4 | 0.304 |
 Uric acid (mg/dL) | 6.6 ± 1.9 | 6.3 ± 2.3 | 0.358 |
 eGFR (ml/min/1.73 m2) | 75.2 ± 28.1 | 84.0 ± 46.3 | 0.319 |