Table 2 Comparison of the results of 1H NMR spectrum between controls and patients with severe extracranial carotid artery stenosis (CAS)
From: Metabolomics study in severe extracranial carotid artery stenosis
| Â | Chemical shift (ppm) | Â | |
|---|---|---|---|
Metabolite ID | Control (n = 65) | CAS (n = 65) | P value |
Formate (8.46) | 0.00235 ± 0.00046 | 0.00222 ± 0.00049 | 0.12583 |
Histidine (7.778) | 0.00756 ± 0.00185 | 0.00764 ± 0.00167 | 0.80616 |
Phenyalanine (7.38) | 0.00767 ± 0.00134 | 0.00781 ± 0.00132 | 0.56561 |
Phenyalanine (7.336) | 0.01426 ± 0.00204 | 0.01485 ± 0.00243 | 0.13568 |
Tyrosine (7.20) | 0.01159 ± 0.00179 | 0.01168 ± 0.00218 | 0.79284 |
Histidine (7.056) | 0.00743 ± 0.00166 | 0.00726 ± 0.00145 | 0.53744 |
Tyrosine (6.906) | 0.01066 ± 0.00164 | 0.01020 ± 0.00197 | 0.15681 |
Lactate (4.125) | 0.09552 ± 0.02848 | 0.11547 ± 0.04951 | 0.00584 |
Creatinine (4.045) | 0.02056 ± 0.00705 | 0.03025 ± 0.03457 | 0.03006 |
Glucose (3.248) | 0.18253 ± 0.03440 | 0.16856 ± 0.04925 | 0.06328 |
Choline (3.205) | 0.14156 ± 0.03223 | 0.12382 ± 0.03109 | 0.00177 |
Glutamine (2.47) | 0.09644 ± 0.01241 | 0.09548 ± 0.01768 | 0.72204 |
Pyruvate (2.365) | 0.03074 ± 0.00577 | 0.02922 ± 0.00602 | 0.14573 |
Lipid (2.23) | 0.12925 ± 0.08064 | 0.12036 ± 0.06102 | 0.47984 |
N-acetylglycoprotein (2.054) | 0.32462 ± 0.11493 | 0.31241 ± 0.08730 | 0.49632 |
Lipid (2.01) | 0.34895 ± 0.11742 | 0.34877 ± 0.13591 | 0.99377 |
Acetate (1.915) | 0.02723 ± 0.00443 | 0.02956 ± 0.01926 | 0.34458 |
Lipid (1.6) | 0.25874 ± 0.16146 | 0.24437 ± 0.12969 | 0.57693 |
Lipid | 0.24517 ± 0.14945 | 0.21435 ± 0.12022 | 0.19762 |
Lactate (1.332) | 0.51526 ± 0.21607 | 0.54140 ± 0.20130 | 0.47661 |
Lipid (1.31) | 3.17346 ± 1.64186 | 2.92170 ± 1.37389 | 0.34491 |
Valine (1.044) | 0.03794 ± 0.01059 | 0.03926 ± 0.01097 | 0.48680 |
Isolecuine (1.005) | 0.01209 ± 0.00389 | 0.01224 ± 0.00349 | 0.82135 |
Leucine (0.965) | 0.02646 ± 0.00641 | 0.02479 ± 0.00567 | 0.11783 |
Lipid (0.90) | 1.59928 ± 0.50784 | 1.42274 ± 0.44536 | 0.03709 |