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Table 2 Comparison of the results of 1H NMR spectrum between controls and patients with severe extracranial carotid artery stenosis (CAS)

From: Metabolomics study in severe extracranial carotid artery stenosis

  Chemical shift (ppm)  
Metabolite ID Control (n = 65) CAS (n = 65) P value
Formate (8.46) 0.00235 ± 0.00046 0.00222 ± 0.00049 0.12583
Histidine (7.778) 0.00756 ± 0.00185 0.00764 ± 0.00167 0.80616
Phenyalanine (7.38) 0.00767 ± 0.00134 0.00781 ± 0.00132 0.56561
Phenyalanine (7.336) 0.01426 ± 0.00204 0.01485 ± 0.00243 0.13568
Tyrosine (7.20) 0.01159 ± 0.00179 0.01168 ± 0.00218 0.79284
Histidine (7.056) 0.00743 ± 0.00166 0.00726 ± 0.00145 0.53744
Tyrosine (6.906) 0.01066 ± 0.00164 0.01020 ± 0.00197 0.15681
Lactate (4.125) 0.09552 ± 0.02848 0.11547 ± 0.04951 0.00584
Creatinine (4.045) 0.02056 ± 0.00705 0.03025 ± 0.03457 0.03006
Glucose (3.248) 0.18253 ± 0.03440 0.16856 ± 0.04925 0.06328
Choline (3.205) 0.14156 ± 0.03223 0.12382 ± 0.03109 0.00177
Glutamine (2.47) 0.09644 ± 0.01241 0.09548 ± 0.01768 0.72204
Pyruvate (2.365) 0.03074 ± 0.00577 0.02922 ± 0.00602 0.14573
Lipid (2.23) 0.12925 ± 0.08064 0.12036 ± 0.06102 0.47984
N-acetylglycoprotein (2.054) 0.32462 ± 0.11493 0.31241 ± 0.08730 0.49632
Lipid (2.01) 0.34895 ± 0.11742 0.34877 ± 0.13591 0.99377
Acetate (1.915) 0.02723 ± 0.00443 0.02956 ± 0.01926 0.34458
Lipid (1.6) 0.25874 ± 0.16146 0.24437 ± 0.12969 0.57693
Lipid 0.24517 ± 0.14945 0.21435 ± 0.12022 0.19762
Lactate (1.332) 0.51526 ± 0.21607 0.54140 ± 0.20130 0.47661
Lipid (1.31) 3.17346 ± 1.64186 2.92170 ± 1.37389 0.34491
Valine (1.044) 0.03794 ± 0.01059 0.03926 ± 0.01097 0.48680
Isolecuine (1.005) 0.01209 ± 0.00389 0.01224 ± 0.00349 0.82135
Leucine (0.965) 0.02646 ± 0.00641 0.02479 ± 0.00567 0.11783
Lipid (0.90) 1.59928 ± 0.50784 1.42274 ± 0.44536 0.03709
  1. Data are presented as mean ± SD. VIP variable importance in the projection