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Table 3 Multivariate analysis of possible predictors of silent brain infarct

From: High triglyceride/HDL cholesterol ratio is associated with silent brain infarcts in a healthy population

 

Crude OR (95% CI)

P-value

Adjusted OR (95% CI)

P-value

Total

Agea

2.28 (1.98 to 2.63)

<  0.001

1.10 (1.09 to 1.12)

<  0.001

Sex

1.07 (0.83 to 1.38)

0.608

1.02 (0.75 to 1.39)

0.890

Hypertension

2.02 (1.55 to 2.65)

<  0.001

1.17 (0.83 to 1.65)

0.037

Diabetes

1.94 (1.42 to 2.64)

<  0.001

1.31 (0.90 to 1.89)

0.157

On antiplatelet medication

1.70 (1.19 to 2.43)

0.003

1.20 (0.80 to 1.79)

0.372

hs-CRPa

1.12 (1.03 to 1.21)

0.008

1.07 (0.96 to 1.18)

0.219

ICAS

2.14 (1.21 to 3.77)

0.009

0.94 (0.44 to 2.00)

0.865

LDL cholesterola

0.83 (0.71 to 0.96)

0.012

0.96 (0.83 to 1.13)

0.637

TG/HDL cholesterol ratioa

1.13 (1.01 to 1.26)

0.030

1.16 (1.00 to 1.34)

0.047

Male

Agea

2.44 (2.02 to 2.94)

<  0.001

1.11 (1.08 to 1.14)

<  0.001

Hypertension

2.27 (1.60 to 3.22)

<  0.001

1.44 (0.92 to 2.24)

0.111

Diabetes

1.69 (1.13 to 2.52)

0.010

1.14 (0.71 to 1.85)

0.587

On antiplatelet medication

1.99 (1.30 to 3.07)

0.002

1.31 (0.79 to 2.16)

0.294

hs-CRPa

1.17 (1.06 to 1.29)

0.002

1.08 (0.96 to 1.22)

0.206

ICAS

2.06 (0.95 to 4.46)

0.068

1.28 (0.49 to 3.32)

0.617

LDL cholesterola

0.74 (0.60 to 0.90)

0.003

0.94 (0.76 to 1.17)

0.590

TG/HDL cholesterol ratioa

1.08 (0.94 to 1.24)

0.289

1.23 (1.03 to 1.48)

0.021

Female

Agea

2.09 (1.69 to 2.59)

<  0.001

1.09 (1.06 to 1.12)

<  0.001

Hypertension

1.72 (1.13 to 2.62)

0.012

0.88 (0.51 to 1.54)

0.656

Diabetes

2.40 (1.47 to 3.93)

<  0.001

1.72 (0.95 to 3.11)

0.073

On antiplatelet medication

1.22 (0.64 to 2.35)

0.546

0.92 (0.45 to 1.86)

0.811

hs-CRPa

1.01 (0.84 to 1.23)

0.898

1.02 (0.82 to 1.27)

0.848

ICAS

2.24 (0.98 to 5.15)

0.057

0.67 (0.19 to 2.39)

0.532

LDL cholesterola

0.95 (0.76 to 1.19)

0.657

1.00 (0.80 to 1.26)

0.989

TG/HDL cholesterol ratioa

1.26 (1.03 to 1.53)

0.023

1.06 (0.82 to 1.36)

0.672

  1. hs-CRP high-sensitivity C-reactive protein, ICAS intracranial atherosclerosis, TG triglyceride, HDL high-density lipoprotein
  2. aThese variables were standardized by division by the standard deviation