Skip to main content

Table 2 Baseline characteristics of the study patients grouped by plasma D-dimer quartile

From: Elevated plasma D-dimer levels are associated with short-term poor outcome in patients with acute ischemic stroke: a prospective, observational study

 

Quartile 1

Quartile 2

Quartile 3

Quartile 4

Pvaluea

(≤ 0.24) n = 226

(0.25–0.56) n = 213

(0.57–1.78) n = 219

(>1.78) n = 219

Age (years), median (IQR)

59 (50–66)

66 (58–74)

66 (53–76)

66 (57–76)

0.000

Sex (male), n (%)

172 (76.1)

152 (71.4)

142 (64.8)

135 (61.6)

0.005

BMI (kg/m2),(Mean ± SD)

24.89 ± 3.52

24.79 ± 3.56

24.99 ± 3.64

25.69 ± 3.78

0.040

Smoker, n (%)

102 (45.1)

90 (42.3)

74 (33.8)

71 (32.4)

0.012

Alcohol drinker, n (%)

56 (24.8)

51 (23.9)

44 (20.1)

41 (18.7)

0.344

Hypertension, n (%)

138 (61.1)

131 (63.5)

130 (59.4)

133 (60.7)

0.972

Diabetes mellitus, n (%)

83 (36.7)

71 (33.3)

55 (25.1)

72 (32.9)

0.062

CAD, n (%)

18 (8.0)

24 (11.3)

27 (12.3)

37 (16.9)

0.036

Atrial fibrillation, n (%)

10 (4.4)

23 (10.8)

30 (13.7)

47 (21.5)

0.000

Dyslipidemia, n (%)

90 (39.8)

80 (37.6)

63 (28.8)

76 (34.7)

0.085

Previous stroke, n (%)

22 (9.7)

38 (17.8)

28 (12.8)

28 (12.8)

0.093

NIHSS on admission, median (IQR)

4 (3–7)

5 (3–7)

6 (3–7)

7 (5–10)

0.000

SBP (mmHg), median (IQR)

148 (134–165)

145 (131–162)

144 (130–162)

152 (134–166)

0.221

DBP (mmHg), median (IQR)

85 (78–95)

82 (76–90)

80 (74–90)

84 (76–93)

0.001

FBG (mmol/L), median (IQR)

5.7 (4.66–8.23)

6.01 (4.95–7.85)

5.90 (4.78–7.46)

6.23 (5.00–9.10)

0.089

D-dimer (mg /L), median (IQR)

0.17 (0.12–0.21)

0.38 (0.31–0.48)

0.92 (0.72–1.27)

3.06 (2.45–3.97)

0.000

Stroke etiology, n (%)

    

0.000

 Large-vessel occlusive

81 (35.8)

82 (38.5)

86 (39.3)

95 (43.4)

 

 Small-vessel occlusive

118 (52.2)

93 (43.7)

91 (41.6)

64 (29.2)

 

 Cardioembolic

7 (3.1)

18 (8.5)

24 (11)

39 (19.8)

 

 Other

12 (5.3)

7 (3.3)

5 (2.3)

6 (2.7)

 

 Unknown

8 (3.5)

13 (6.1)

13 (5.9)

15 (6.8)

 

Mortality, n (%)

4 (1.8)

13 (6.1)

24 (11)

36 (16.4)

0.000

  1. BMI body mass index, CAD coronary artery disease, NIHSS National Institutes of Health Stroke Scale, SBP systolic blood pressure, DBP diastolic blood pressure, IQR interquartile range, SD standard deviation
  2. a P value was assessed χ2 test, ANOVA or Mann–Whitney U tests, as appropriate