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Table 1 The baseline demographics, clinical characteristics and biochemical variables between the two groups

From: The combined presence of hypertension and vitamin D deficiency increased the probability of the occurrence of small vessel disease in China

Variables SVD (N = 106) Control (N = 115) P
Demographics
 Age (Y) 61.6 ± 13.2 60.5 ± 11.7 0.516
 Sex (Male, %) 80(75.5%) 54(47%) 0.001*
 Systolic blood pressure 151.5 ± 21 133.7 ± 17.3 0.001*
 Diastolic blood pressure 87 ± 14.2 80.1 ± 12.3 0.001*
Risk factors
 Hypertension 66(62.3%) 75(65.2%) 0.648
 Diabetes mellitus 33(31.1%) 26(22.6%) 0.152
 Coronary disease 11(10.4%) 16(13.9%) 0.423
 Prior stroke 26(24.5%) 5(4.3%) 0.001*
 Hyperlipidaemia 79(74.5) 31(27%) 0.001*
 Atrial fibrillation 2(2.3%) 2(6.7%) 0.251
 Peripheral arterial disease 6(5.7%) 3(2.6%) 0.252
 Smoking 60(56.6%) 45(39.1%) 0.010*
Blood tests
 White blood cell (109/L) 7.1 ± 2.1 6.9 ± 2.1 0.514
 Red blood cell (1012/L) 4.6 ± 0.6 4.6 ± 0.6 0.773
 Platelet (109/L) 210.8 ± 92.6 221.7 ± 55.7 0.290
 Total cholesterol (mmol/L) 4.4 ± 0.9 4.3 ± 0.8 0.259
 Low-density lipoprotein (mmol/L) 2.7 ± 0.8 2.4 ± 0.8 0.003*
 High-density lipoprotein (mmol/L) 1.1 ± 0.3 1.1 ± 0.3 0.103
 Uric acid(μmol/L) 329.8 ± 87.9 330.3 ± 95.9 0.972
 Homocysteine(μmol/L) 18.9 ± 10.5 18 ± 12.3 0.610
 Fasting blood glucose (mmol/L) 5.9 ± 1.8 5.6 ± 1.3 0.231
 Hemoglobin A1c (%) 6.4 ± 1.4 6.3 ± 1.2 0.737
 Glycated albumin(%) 13.8 ± 2.4 17.5 ± 3.8 0.060
 Fibrinogen(mg/dl) 268.5 ± 82.2 271.8 ± 87.3 0.843
 C-reactive protein (mg/L) 2.05(1.2~4.0) 2.25(0.89~4.56) 0.925
 25-hydroxy vitamin D (ng/mL) 10.2 ± 5.6 14.6 ± 7.5 0.001*
 Albumin (g/L) 42.1 ± 4.4 42.5 ± 4.8 0.681
  1. Values represent number (percent) for categorical variables and mean ± SD or median (interquartile range) for continuous variables. *P < 0.05 is statistically significant