Anti-AchR Ab titer < 0.2 nmol/L (n = 15) | Anti-AchR Ab titer ≥0.2 and < 0.5 nmol/L (n = 8) | Anti-AchR Ab titer ≥0.5 nmol/L (n = 31) | p | ||
---|---|---|---|---|---|
n (%) | n (%) | n (%) | |||
Sex | Female | 7 (46) | 4 (50) | 19 (61) | 0.69 |
Male | 8 (54) | 4 (50) | 12 (39) | ||
Age | < 10 year | 8 (53) | 6 (75) | 22 (71) | 0.52 |
11~20 year | 7 (46) | 2 (25) | 9 (29) | ||
Symptoms at onset | Ptosis | 15 (100) | 8 (100) | 29 (94) | 1.00 |
Diurnal change | 10 (67) | 4 (50) | 19 (61) | 0.80 | |
Diplopia | 5 (33) | 2 (25) | 4 (13) | 0.44 | |
Bulbar sign | 3 (23) | 0 (0) | 5 (19) | 0.73 | |
Respiratory symptoms | 1 (7) | 0 (0) | 3 (11) | 1.00 | |
Clinical subtype | Ocular type | 10 (67) | 8 (100) | 24 (77) | 0.22 |
Generalized type | 5 (33) | 0 (0) | 7 (23) | ||
aMGFA classification | 0.41 | ||||
I | 10 (67) | 8 (100) | 24 (77) | ||
II | 4 (27) | 0 (0) | 3 (10) | ||
III | 1 (6) | 0 (0) | 1 (3) | ||
IV | 0 (0) | 0 (0) | 3 (10) | ||
V | 0 (0) | 0 (0) | 0 | ||
Ethnicity | Chinese | 15 (100) | 8 (100) | 31 (100) | 1.00 |
Co-morbid diseases | Thymus hyperplasia | 6 (40) | 3 (37.5) | 10 (32) | 0.89 |
Hyperthyroidism | 1 (6.7) | 1 (13) | 6 (19) | 0.66 | |
Thymoma | 0 | 0 | 1 (3) | NA | |
Treatment | Total | 14 (93) | 8 (100) | 31 (100) | 0.42 |
Thymectomy | 2 (13) | 2 (25) | 7 (23) | 0.71 | |
Prednisolone only | 1 (6.7) | 0 | 2 (6.5) | 1.00 | |
Anti-cholinergic regimen only | 6 (40) | 4 (50) | 7 (23) | 0.23 | |
Both prednisolone and anti-cholinergic regimen | 5 (33) | 2 (25) | 15 (48) | 0.44 |