Table 1 Overview of inclusion and exclusion criteria
Inclusion criterion | Measured with | Defined by |
Significant subjective cognitive complaints | Parkinson’s Disease Cognitive Functional Rating Scale | Score > 3 |
Mild to moderate disease stage | Hoehn & Yahr disease stage | Score < 4 |
Access to computer or tablet with access to Internet. Capability to use keyboard and computer mouse | Phone interview | – |
Signed informed consent | – | – |
General exclusion criterion | Measured with | Defined by |
Indication for dementia syndrome | Self-administered Gerocognitive Examination | Score < 14 |
Montreal Cognitive Assessment | Score < 22 | |
Current drug- or alcohol abuse | CAGE AID-interview | Score > 1 |
Inability to undergo extensive neuropsychological assessments or eight weeks of home-based cognitive intervention | – | – |
Moderate to severe depressive symptoms | Beck depression inventory | Score > 18 |
Presence of one or more impulse control disorders | ICD criteria interview | Positive screening |
Psychotic symptoms. Benign hallucinations with insight are not an exclusion criterion | Schedule for Assessment of Positive Symptoms – PD | Positive screening |
Traumatic brain injury | Phone interview | Cerebral contusion with 1) loss of consciousness for > 15 min and 2) posttraumatic amnesia > 1 h |
Exclusion criterion for participation in magnetic resonance imaging | Measured with | Defined by |
A space occupying lesion | Assessment by radiologist | – |
Significant vascular abnormalities | Assessment by radiologist | Fazekas > 1 |
Severe claustrophobia | MRI safety screening questionnaire | Positive screening |
Presence of metal in the body (e.g. pacemaker, neurostimulator) | ||
Pregnancy | ||
Difficulty with, or shortness of breath during 60 min of lying still |