Skip to main content

Table 3 Risk of poor IS outcome per unit increase in log HOMA-IR

From: Homeostasis model assessment of insulin resistance and outcome of ischemic stroke in non-diabetic patients - a prospective observational study

 

n

Crude

Model A

Model B

Acute HOMA-IR

 3 months

423

1.50 (1.07–2.11)*

1.69 (1.16–2.46)**

1.12 (0.60–2-06)

 2 years

436

1.22 (0.86–1.71)

1.32 (0.90–1.92)

0.89 (0.51–1.55)

 7 years Deaths (mRS 6) included

294

1.59 (1.11–2.30)*

2.01 (1.31–3.10)**

1.75 (0.97–3.16)

 7 years Deaths (mRS 6) excluded

254

1.50 (0.96–2.33)††

1.72 (1.03–2.87)*

1.23 (0.59–2.57)

3 months HOMA-IR

 3 months

420

1.25 (0.84–1.85)

1.53 (0.95–2.45)

1.27 (0.69–2.42)

 2 years

426

1.15 (0.77–1.71)

1.24 (0.77–1.98)

1.04 (0.56–1.94)

 7 years Deaths (mRS 6) included

289

0.97 (0.64–1.48)

1.03 (0.61–1.74)

0.91 (0.49–1.70)

 7 years Deaths (mRS 6) excluded

257

0.93 (0.56–1.55)

0.80 (0.43–1.50)

0.70 (0.31–1.58)

  1. Footnote: Odds ratios (ORs) and 95% confidence intervals (CIs) of having a poor outcome (mRS ≥3) at different time points after IS stroke per unit increase in log-HOMA-IR. Adjusted ORs for covariates. Model A: age, sex, BMI, hypertension, LDL and smoking. Model B: age, sex, BMI, hypertension, LDL, smoking and stroke severity (acute NIHSS). p = 0.06, ††p = 0.07, p = 0.08 *p < 0.05, **p < 0.01