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Table 2 Predictors of vascular outcome, recurrent stroke, and death in 686 patients (univariate analysis)

From: Risk factors outperform intracranial large artery stenosis predicting unfavorable outcomes in patients with stroke

 

Vascular outcome

Recurrent stroke

Death

Hazard Ratio (95%CI)

P Value

Hazard Ratio (95%CI)

P Value

Hazard Ratio (95%CI)

P Value

Age, y

  ≤ 64

1

  

1

  

1

  

  ≥ 65

1.169

(.762–1.792)

.474

1.140

(.666–1.953)

.633

1.449

(.802–2.618)

.219

Sex

 Female

1

  

1

  

1

  

 Male

1.026

(.667–1.578)

.907

1.218

(.697–2.129)

.490

.526

(.304–.912)

.022

Body mass index, kg/m2

  < 24

1

  

1

  

1

  

 24–27

.740

(.464–1.179)

.205

.820

(.453–1.482)

.511

.800

(.438–1.461)

.467

  ≥ 27

.600

(.336–1.071)

.084

.762

(.379–1.530)

.444

.418

(.173–1.008)

.052

Carotid artery stenosis

  ≤ 50%

1

  

1

  

1

  

  > 50%

1.072

(.495–2.320)

0.860

1.488

(.638–3.470)

0.358

0.044

(0–6.445)

.220

Glomerular filtration rate

  ≥ 60

1

  

1

  

1

  

 30–59

1.305

(.840–2.029)

.237

1.171

(.683–2.008)

0.567

1.956

(1.039–3.684)

.038

  < 30

2.181

(1.117–4.258)

.022

1.048

(.367–2.992)

0.931

4.958

(2.298–10.695)

<.001

Uric acid

 Normal

1

  

1

  

1

  

 Abnormal

1.583

(.879–2.851)

.126

1.495

(.707–3.160)

.293

2.269

(1.132–4.545)

.021

Hypertension

2.094

(1.203–3.642)

.009

2.187

(1.073–4.457)

.031

1.178

(.628–2.212)

.610

Diabetes mellitus

1.375

(.912–2.075)

.129

1.231

(.731–2.073)

.435

1.753

(1.010–3.044

.046

Hyperlipidemia

1.023

(.675–1.550)

.914

1.141

(.672–1.937)

.625

.861

(.497–1.492)

.594

Heart disease

1.678

(1.095–2.574)

.018

1.143

(.641–2.037)

.651

2.226

(1.279–3.875)

.005

Atrial fibrillation

1.466

(.709–3.033)

.302

.512

(.125–2.102)

.353

2.345

(1.055–5.213)

.036

Smoking

.923

(.600–1.420)

.715

.942

(.547–1.625)

.831

.540

(.282–1.031)

.062

Baseline NIHSS

 0–6

1

  

1

  

1

  

 7–15

.766

(.411–1.428)

.401

.754

(.395–1.440)

.392

2.709

(1.306–5.620)

.007

 16–38

.765

(.379–1.547)

.456

.774

(.305–1.961)

.588

10.003

(5.116–19.561)

<.001

Old infarction

1.804

(1.087–2.992)

.022

1.572

(.846–2.921)

.152

1.843

(.923–3.680)

.083

Stenosis state

 ILAS-

1

  

1

  

1

  

 ILAS+AS

1.657

(.951–2.886)

.075

1.370

(.622–3.018)

.435

2.115

(.996–4.963)

.051

 ILAS+S

.977

(.608–1.568)

.922

1.384

(.788–2.431)

.258

1.585

(.895–2.924)

.141

Multiple stenosis

1.213

(.773–1.901)

.401

1.224

(.694–2.158)

.486

1.555

(.875–2.761)

.132

Subtypes of stroke

 Small vessel occlusive

–

  

1

 

.595

–

  

 Atherosclerosis

–

–

–

.483

(.035–6.636)

.587

–

–

–

 Cardioembolism

–

–

–

.909

(.075–11.027)

.941

–

–

–

  1. § ILAS Intracranial Large Artery Stenosis, ILAS+S symptomatic ILAS, ILAS+AS asymptomatic ILAS, NIHSS National Institutes of Health Stroke Scale