| Vascular outcome | Recurrent stroke | Death | ||||||
---|---|---|---|---|---|---|---|---|---|
Hazard Ratio (95%CI) | P Value | Hazard Ratio (95%CI) | P Value | Hazard Ratio (95%CI) | P Value | ||||
Age, y | |||||||||
  ≤ 64 | 1 |  |  | 1 |  |  | 1 |  |  |
  ≥ 65 | 1.169 | (.762–1.792) | .474 | 1.140 | (.666–1.953) | .633 | 1.449 | (.802–2.618) | .219 |
Sex | |||||||||
 Female | 1 |  |  | 1 |  |  | 1 |  |  |
 Male | 1.026 | (.667–1.578) | .907 | 1.218 | (.697–2.129) | .490 | .526 | (.304–.912) | .022 |
Body mass index, kg/m2 | |||||||||
  < 24 | 1 |  |  | 1 |  |  | 1 |  |  |
 24–27 | .740 | (.464–1.179) | .205 | .820 | (.453–1.482) | .511 | .800 | (.438–1.461) | .467 |
  ≥ 27 | .600 | (.336–1.071) | .084 | .762 | (.379–1.530) | .444 | .418 | (.173–1.008) | .052 |
Carotid artery stenosis | |||||||||
  ≤ 50% | 1 |  |  | 1 |  |  | 1 |  |  |
  > 50% | 1.072 | (.495–2.320) | 0.860 | 1.488 | (.638–3.470) | 0.358 | 0.044 | (0–6.445) | .220 |
Glomerular filtration rate | |||||||||
  ≥ 60 | 1 |  |  | 1 |  |  | 1 |  |  |
 30–59 | 1.305 | (.840–2.029) | .237 | 1.171 | (.683–2.008) | 0.567 | 1.956 | (1.039–3.684) | .038 |
  < 30 | 2.181 | (1.117–4.258) | .022 | 1.048 | (.367–2.992) | 0.931 | 4.958 | (2.298–10.695) | <.001 |
Uric acid | |||||||||
 Normal | 1 |  |  | 1 |  |  | 1 |  |  |
 Abnormal | 1.583 | (.879–2.851) | .126 | 1.495 | (.707–3.160) | .293 | 2.269 | (1.132–4.545) | .021 |
Hypertension | 2.094 | (1.203–3.642) | .009 | 2.187 | (1.073–4.457) | .031 | 1.178 | (.628–2.212) | .610 |
Diabetes mellitus | 1.375 | (.912–2.075) | .129 | 1.231 | (.731–2.073) | .435 | 1.753 | (1.010–3.044 | .046 |
Hyperlipidemia | 1.023 | (.675–1.550) | .914 | 1.141 | (.672–1.937) | .625 | .861 | (.497–1.492) | .594 |
Heart disease | 1.678 | (1.095–2.574) | .018 | 1.143 | (.641–2.037) | .651 | 2.226 | (1.279–3.875) | .005 |
Atrial fibrillation | 1.466 | (.709–3.033) | .302 | .512 | (.125–2.102) | .353 | 2.345 | (1.055–5.213) | .036 |
Smoking | .923 | (.600–1.420) | .715 | .942 | (.547–1.625) | .831 | .540 | (.282–1.031) | .062 |
Baseline NIHSS | |||||||||
 0–6 | 1 |  |  | 1 |  |  | 1 |  |  |
 7–15 | .766 | (.411–1.428) | .401 | .754 | (.395–1.440) | .392 | 2.709 | (1.306–5.620) | .007 |
 16–38 | .765 | (.379–1.547) | .456 | .774 | (.305–1.961) | .588 | 10.003 | (5.116–19.561) | <.001 |
Old infarction | 1.804 | (1.087–2.992) | .022 | 1.572 | (.846–2.921) | .152 | 1.843 | (.923–3.680) | .083 |
Stenosis state | |||||||||
 ILAS- | 1 |  |  | 1 |  |  | 1 |  |  |
 ILAS+AS | 1.657 | (.951–2.886) | .075 | 1.370 | (.622–3.018) | .435 | 2.115 | (.996–4.963) | .051 |
 ILAS+S | .977 | (.608–1.568) | .922 | 1.384 | (.788–2.431) | .258 | 1.585 | (.895–2.924) | .141 |
Multiple stenosis | 1.213 | (.773–1.901) | .401 | 1.224 | (.694–2.158) | .486 | 1.555 | (.875–2.761) | .132 |
Subtypes of stroke | |||||||||
 Small vessel occlusive | – |  |  | 1 |  | .595 | – |  |  |
 Atherosclerosis | – | – | – | .483 | (.035–6.636) | .587 | – | – | – |
 Cardioembolism | – | – | – | .909 | (.075–11.027) | .941 | – | – | – |