Table 3 Multivariate Cox proportional-hazard regression analysis for vascular outcome, recurrent stroke, and death (N = 685)
| Â | Vascular outcome | Recurrent stroke | Death | ||||||
|---|---|---|---|---|---|---|---|---|---|
Hazard Ratio (95%CI) | P Value | Hazard Ratio (95%CI) | P Value | Hazard Ratio (95%CI) | P Value | ||||
Age, y | |||||||||
  ≤ 64 | – |  |  | – |  | – | – |  |  |
  ≥ 65 | – |  |  | – |  | – | – |  |  |
Sex | |||||||||
 Female | 1 |  |  | – |  | – | 1 |  |  |
 Male | 1.146 | (.685–1.918) | .605 | – |  | – | .681 | .311–1.492 | .337 |
Body mass index, kg/m2 | |||||||||
  < 24 | 1 |  |  | – |  | – | – |  |  |
 24–27 | .587 | (.354–.974) | .039 | – |  | – | – |  |  |
  ≥ 27 | .550 | (.303–.997) | .049 | – |  | – | – |  |  |
Carotid artery stenosis | |||||||||
  ≤ 50% | – |  |  | – |  | – | – |  |  |
  > 50% | – |  |  | – |  | – | – |  |  |
Glomerular filtration rate | |||||||||
  ≥ 60 | – |  |  | – |  | – | 1 |  |  |
 30–59 | – |  |  | – |  | – | 1.965 | .875–4.415 | .102 |
  < 30 | – |  |  | – |  | – | 3.793 | 1.357–10.596 | .011 |
Uric acid | |||||||||
 Normal | 1 |  |  | – |  | – | 1 |  |  |
 Abnormal | 1.697 | (.881–3.271) | .114 | – |  | – | 2.021 | .842–4.854 | .115 |
Hypertension | 2.176 | (1.202–3.939) | .010 | 2.200 | (1.058–4.576) | .035 | – |  |  |
Diabetes mellitus | – |  |  | – |  | – | – |  |  |
Hyperlipidemia | – |  |  | – |  | – | – |  |  |
Heart disease | – |  |  | – |  | – | – |  |  |
Atrial fibrillation | – |  |  | – |  | – | – |  |  |
Smoking | .773 | (.460–1.300) | .332 | .701 | (.374–1.315) | .269 | – |  |  |
Baseline NIHSS | |||||||||
 0–6 | 1 |  |  | – |  | – | 1 |  |  |
 7–15 | .936 | (.551–1.589) | .806 | – |  | – | 2.011 | .898–4.504 | .089 |
 16–38 | 1.438 | (.711–2.908) | .312 | – |  | – | 9.978 | 4.345–22.914 | <.001 |
Old infarction | 1.735 | (1.008–2.987) | .047 | – |  | – | 1.393 | .560–3.465 | .476 |
Stenosis state | |||||||||
 ILAS- | 1 |  |  | – |  | – | 1 |  |  |
 ILAS+AS | 1.180 | (.650–2.139) | .587 | – |  | – | 1.644 | .688–4.048 | .280 |
 ILAS+S | .842 | (.506–1.402) | .508 | – |  | – | .886 | .408–1.927 | .760 |
Multiple stenosis | – |  |  | – |  | – | – |  |  |
Subtypes of stroke | |||||||||
 Small vessel occlusive | – |  |  | – |  | – | – |  |  |
 Atherosclerosis | – | – | – | – |  | – | – | – | – |
 Cardioembolism | – | – | – | – |  | – | – | – | – |