Remote ischemic conditioning improves cognition in patients with subcortical ischemic vascular dementia

BMC Neurology

Table 3 Covariance analysis of efficacy between the Two Groups

Psychometric scores	RIC Group(n = 18)	Control Group(n = 19)	p
HVLT-R
HVLT1	17.02 ± 1.05	15.93 ± 1.02	0.464
HVLT2	4.68 ± 0.73	4.56 ± 0.71	0.908
HVLT3	8.78 ± 0.50	7.47 ± 0.48	0.069
COWAT	6.35 ± 0.62	5.57 ± 0.60	0.372
TMT-A	105.12 ± 13.09	125.70 ± 13.47	0.282
TMT-B	201.64 ± 17.29	204.80 ± 17.29	0.898
SDMT	22.82 ± 1.68	20.07 ± 1.68	0.259
JLO	23.10 ± 1.23	18.56 ± 1.23	0.013
Hs-CRP	2.63 ± 0.74	1.19 ± 0.83	0.220
IL-6	15.85 ± 6.70	15.81 ± 4.27	0.790
TNF-α	5.57 ± 1.02	5.46 ± 0.72	0.679
WMLV (cm³)	74.21 ± 4.24	65.18 ± 3.79	0.166
WBWM
FA	0.291 ± 0.009	0.306 ± 0.009	0.336
MD(×10⁻⁴)	9.5 ± 0.32	9.0 ± 0.71	0.658
NAWM
FA	0.292 ± 0.01	0.307 ± 0.01	0.358
MD(×10⁻⁴)	9.3 ± 0.46	8.9 ± 0.62	0.485

Abbreviations: COWAT Controlled Oral Word Association Test, the outcome was the sum of correct words in the both parts, FA fractional anisotropy, hs-CRP high-sensitive C-reactive protein, HVLT1 immediate memory of Hopkins Verbal Learning Test-Revised (HVLT-R), HVLT2 delayed memory of HVLT-R, HVLT3 recognition test of HVLT-R, IL-6 interleukin 6, JLO Judgment of Line Orientation, MD mean diffusivity, NAWM normal-appearing white matter, SDMT Symbol Digit Modalities Test, TMT-A Trail Making Test A, TMT-B Trail Making Test B, TNF-α tumor necrosis factor-alpha, WBWM whole-brain white matter, WMLV white matter lesion volume

ISSN: 1471-2377