Table 4 Clinical features of ALS patients with short and long survival
Characteristic | Short survival (n = 22) | Long survival (n = 23) | OR (95% CI) |
|---|---|---|---|
Age at onset (years), mean (range) | 61.50 (42–82) | 54.87 (38–78) | NA |
Age group | 0.91 (0.30–2.79) | ||
< 60 years, n (%) | 11 (50) | 12 (52.17) | |
> 60 years, n (%) | 11 (50) | 11 (47.82) | |
Gender | 2.25 (0.63–7.45) | ||
Males, n (%) | 12 (54.54) | 8 (34.78) | |
Females, n (%) | 10 (45.45) | 15 (65.21) | |
Weight at diagnosis (Kg), mean (SD) | 52.14 (11.61) | 49.22 (12.52) | NA |
Weight loss (Kg), mean (SD) | 10.77 (5.30) | 12.86 (6.83) | 1.07 (0.35–3.32) |
<10 kg, n (%) | 9 (40.90) | 9 (39.13) | |
>10 kg, n (%) | 13 (59.09) | 14 (60.86) | |
Comorbidities | 0.48 (0.13–1.80) | ||
Yes, n (%) | 8 (36.36) | 5 (21.73) | |
No, n (%) | 14 (63.63) | 18 (78.26) | |
ODI (mo), mean (SD) | 14.27 (8.44) | *** 29.83 (18.80) | 14.48 (3.38–53.99) |
<24 mo, n (%) | 19 (86.36) | 7 (30.43) | |
>24 mo, n (%) | 3 (13.63) | 16 (69.56) | |
PEG, n (%) | 17 (77.27) | 14 (60.86) | 2.18 (0.62–7.65) |
OGI (mo), mean (SD) | 10.94 (8.43) | **27.93 (22.20) | 11.92 (2.27–50.84) |
<18 mo, n (%) | 13 (76.47) | 3 (21.42) | |
>18 mo, n (%) | 4 (23.52) | 11 (78.57) | |
MV, n (%) | 21 (95.45) | 11 (47.82) | 22.91 (2.88–254.80) |
OMVI (mo), mean (SD) | 17.33 (7.73) | *45.00 (20.93) | 2.33 (0.58–8.66) |
<24 mo, n (%) | 12 (57.14) | 4 (36.36) | |
>24 mo, n (%) | 9 (42.85) | 7 (63.63) | |
Total cholesterol at onset (mmol/L) | 4.13 (0.72) | **5.31 (1.20) | 7.33 (1.29–33.10) |
< 4.63 mmol/L, n (%) | 11 (73.33) | 3 (27.27) | |
>4.63 mmol/L, n (%) | 4 (26.66) | 8 (72.72) | |