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Table 3 Multi-adjusteda odds ratio (OR) with 95% confidence interval (CI) of elevated high sensitivity C-reactive protein (hs-CRP) defined as > 3.0–20.0 mg/l related to headache types and insomnia status

From: The impact of C-reactive protein levels on headache frequency in the HUNT study 2006–2008

  Total Without insomnia With insomnia
N OR (95% CI) N OR (95% CI)
No headache 24,823 23,766 1.00 1057 1.00
Any headache 13,990 12,359 1.07 (1.01–1.13) 1631 0.83 (0.68–1.01)
Migraine 3793 3196 1.12 (1.02–1.24) 597 0.99 (0.76–1.20)
MA 2139 1777 1.19 (1.06–1.35) 362 0.97 (0.71–1.33)
MO 1654 1419 1.06 (0.92–1.22) 235 1.02 (0.72–1.45)
Other headaches 10,197 9163 1.06 (0.99–1.13) 1034 0.77 (0.62–0.96)
  1. MA Migraine with aura, MO Migraine without aura aAdjusted for age, sex, body mass index, smoking, employment status, alcohol use, physical activity and Hospital Anxiety and Depression Scale score