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Table 3 Multi-adjusteda odds ratio (OR) with 95% confidence interval (CI) of elevated high sensitivity C-reactive protein (hs-CRP) defined as > 3.0–20.0 mg/l related to headache types and insomnia status

From: The impact of C-reactive protein levels on headache frequency in the HUNT study 2006–2008

 

Total

Without insomnia

With insomnia

N

OR (95% CI)

N

OR (95% CI)

No headache

24,823

23,766

1.00

1057

1.00

Any headache

13,990

12,359

1.07 (1.01–1.13)

1631

0.83 (0.68–1.01)

Migraine

3793

3196

1.12 (1.02–1.24)

597

0.99 (0.76–1.20)

MA

2139

1777

1.19 (1.06–1.35)

362

0.97 (0.71–1.33)

MO

1654

1419

1.06 (0.92–1.22)

235

1.02 (0.72–1.45)

Other headaches

10,197

9163

1.06 (0.99–1.13)

1034

0.77 (0.62–0.96)

  1. MA Migraine with aura, MO Migraine without aura aAdjusted for age, sex, body mass index, smoking, employment status, alcohol use, physical activity and Hospital Anxiety and Depression Scale score