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Table 1 Comparison of baseline characteristics between patients with no prestroke statins use prestroke statins use groups

From: Prestroke statins use reduces oxidized low density lipoprotein levels and improves clinical outcomes in patients with atrial fibrillation related acute ischemic stroke

  No prestroke statins use group (136) Prestroke Statins use group (106) OR(95% CI) P*
Age, y (Mean SD) 66.1 ± 10.5 67.2 ± 9.9   0.303
NIHSS score, median (IQR) 11 (7–14) 8(6–12)   0.041
Mean AF duration, m (Mean SD) 67.7 ± 10.0 67.8 ± 11.3   0.915
CHA2DS2-VASc, median (IQR) 4(3–5) 4(3–5)   0.090
Females, n (%) 66 (48.5%) 58 (54.7%) 1.29 (0.77–2.13) 0.339
Men, n (%) 70 (51.5% 48 (45.3%) 1.29 (0.77–2.13) 0.339
BMI ≥ 24 kg/m, n (%) 36 (26.5%) 37 (34.9%) 1.50 (0.86–2.59) 0.156
Hypertension, patients, n (%) 90 (66.8%) 79 (74.5%) 1.50 (0.85–2.63) 0.160
Current Smoking, n (%) 46 (33.8%) 30 (28.3%) 0.77 (0.45–1.34) 0.359
Current alcohol consumption, n (%) 41 (30.2%) 24 (22.6%) 0.67 (0.38–1.22) 0.191
Diabetes, n (%) 37 (27.2%) 31 (29.2%) 1.11 (0.63–1.94) 0.736
Hyperlipidemia, n (%) 40 (29.4%) 79 (74.5%) 7.02 (3.96–12.4) < 0.001
AF Type
 Paroxysmal, n (%) 47(34.6) 38(35.8) 0.95(0.56–1.61) 0.835
 Permanent, n (%) 89(65.4) 68(64.2) 0.95(0.56–1.61) 0.835
 Family history of stroke, n (%) 28 (20.6%) 23 (21.7%) 1.07 (0.57–1.99) 0.834
 Ox-LDL,U/L (Mean SD) 37.6 ± 5.1 33.5 ± 5.5   < 0.001
Medication use
 Warfarin, n (%) 20 (14.7%) 19 (17.9%) 1.27 (0.64–2.52) 0.499
 direct oral anticoagulants, n (%) 10(7.4%) 8(7.5%) 1.03(0.39–2.70) 0.954
 antiplatelets, n (%) 25(18.4) 15(14.2) 0.73(0.36–1.45) 0.379
 Antihypertensive, n (%) 76 (55.9%) 58 ((54.7%) 0.95 (0.57–1.59) 0.856
  1. Bold indicates P-values less than 0.05
  2. *Comparison between no prestroke statins use and prestroke statins use groups. The data are presented as median values (interquartile range [IQR]), numbers (%), or mean values (±standard deviation). Categorical variables are expressed as frequency (percent) for P values. Baseline characteristics were compared between the 2 subgroups by univariate analysis using Pearson χ2, distributions of continuous variables were determined by the Kolmogorov–Smirnov test, Mann–Whitney two sample test was applied in case of non-normal distributions