Table 1 Subject Characteristics
Control (n = 216) | Stroke within 24 h (n = 458) | Stroke on day 10 (n = 320) | p | |
|---|---|---|---|---|
Demographic | ||||
Age, y, mean (SD) | 68.14 (0.89) | 67.56 (1.65) | 67.94 (1.15) | 0.596 |
Male gender, n (%) | 121 (56) | 243 (55) | 208 (65) | 0.258 |
Medical history, n (%) | ||||
Hypertension | 63 (29.2) | 142 (31.0) | 104 (32.5) | 0.705 |
DM | 69 (31.9) | 103 (22.5) | 90 (28.8) | 0.626 |
History of smoking | 52 (24.1) | 90 (19.7) | 91 (28.4) | 0.229 |
History of alcohol | 43 (20.0) | 110 (24.0) | 70 (21.9) | 0.926 |
Plasma lipids | ||||
TC, mmol/L (SD) | 4.68 (0.76) | 4.70 (0.84) | 4.50 (0.51) | 0.586 |
HDL, mmol/L (SD) | 1.19 (0.08) | 1.12 (0.09) | 1.32 (0.02) | 0.732 |
LDL, mmol/L (SD) | 2.89 (0.05) | 2.95 (0.54) | 2.91 (0.24) | 0.510 |
TG, mmol/L (SD) | 1.53 (0.56) | 1.41 (0.62) | 1.29 (0.21) | 0.675 |
Inflammatory biomarkers | ||||
hsCRP, mg/L (SD) | 1.98 (0.35) | 10.12 (0.58) | 3.56 (0.51) | 0.029* |
WBCC, 103/ml (SD) | 5.4 (0.8) | 9.8 (0.8) | 4.8 (0.7) | 0.033* |
D-dimer, ng/mL (SD) | 549.84 (85.84) | 697.92 (181.48) | 642.84 (92.81) | 0.184 |
Fibrinogen, g/L (SD) | 2.49 (0.17) | 2.72 (0.11) | 2.92 (0.03) | 0.849 |
Stroke subtype, n (%) | 0.449 | |||
Large artery atherosclerosis | 188 (41.0) | 124 (38.7) | ||
Microangiopathy | 90 (19.7) | 56 (17.5) | ||
Cardioembolism | 126 (27.5) | 102 (31.9) | ||
Unknown | 54 (11.8) | 38 (11.9) | ||
Stroke syndrome | 0.346 | |||
LACS | 126 (27.5) | 43 (13.4) | ||
TACS | 53 (11.6) | 57 (17.6) | ||
PACS | 174 (38.0) | 131 (41.2) | ||
POCS | 105 (22.9) | 89 (27.8) | ||
Neurological scores at admission, median (IQR) | ||||
NIHSS | 8 (2–24) | 2 (0–6) | < 0.001* | |
mRS | 3 (1–5) | 1 (0–2) | < 0.001* | |