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Table 1 Clinical characteristics of MG patients with disseminated nocardiosis

From: A case report of disseminated nocardiosis with ocular involvement in a myasthenia gravis patient and literature review

Case

Age /sex

Author/year

Symptoms

Underlying disease

Immune suppression

Operation

Sites of disease

Treatments

Outcome

1

59/male

Kim 2002

skin lesions, fever, cough

MG, thymoma

prednisolone

thymectomy

skin, lung

TMP-SMX

resolution

2

49/male

El-Herte 2012

Fever, chills, chest pain, weight loss

MG, thymoma

prednisone

thymectomy

lung, brain, heart

imipenem, amikacin, TMP-SMX

resolution

3

59/female

Tanioka 2012

Malaise, cough

MG

prednisolone, tacrolimus, cyclosporine

NA

lung, kidney, brain

imipenem-cilastatin, TMP-SMX, minocycline, meropenem, amikacin, linezolid

resolution

4

79/male

Patel 2013

left leg pain, cough

MG

prednisone

NA

leg, lung

moxifloxacin

NA

5

77/male

Garcia 2015

night sweats, cough

MG, TB

prednisone, plasmapheresis

thymectomy

lung, brain

TMP-SMX, meropenem, linezolid

resolution

6

79/male

Veerappan 2015

leg abscesses

MG

steroid

NA

lung, muscle

vancomycin, piperacillin-tazobactam, ampicillin, ceftriaxone, doxycycline, moxifloxacin, linezolid

resolution

7

52/male

Wargo 2015

cough, dyspnoea, weight loss, subcutaneous nodules, fatigue

MG, thymoma, Good’s syndrome

prednisone, chemotherapy, radiation

NA

lung, skin, brain

meropenem, TMP-SMX, imipenem, linezolid

resolution

8

66/male

Wang 2019

fever, dyspnoea, headache, pain on left eye and right leg, skin ulcer, blindness, muscle strength decreased

MG, hypertension, diabetes

methylprednisolone, azathioprine

None

Lung, brain, skin, ocular

TMP-SMX, etimicin sulfate, moxifloxacin, ceftriaxone, imipenem, meropenem

resolution

  1. Abbreviations: MG myasthenia gravis, TMP-SMX trimethoprim-sulfamethoxazole, TB tuberculosis, NA not available