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Table 1 Baseline Characteristics of Participants, the ARIC Study (1990–1992)

From: Mid-life serum Vitamin D concentrations were associated with incident dementia but not late-life neuropsychological performance in the Atherosclerosis Risk in Communities (ARIC) Study

Baseline characteristics Overall 25(OH) D (ng/mL)
≥30 (Sufficient) 20- < 30 (Intermediate) < 20 (Deficient)
N 13,039 3046 5759 4234
25(OH) D (ng/mL), b range 0.5–108.7 30–108.7 20- < 30 0.5- < 20
25(OH) D (ng/mL),b mean (SD) 24.3 (8.6) 35.8 (5.9) 24.8 (2.8) 15.3 (3.5)
Age (years), mean (SD) 57.4 (5.7) 57.9 (5.7) 57.6 (5.7) 56.9 (5.7)
Women, n (%) 7384 (56.6%) 1490 (48.9%) 2998 (52.1%) 2896 (68.4%)
Race/Center, n (%)
 Minneapolis, MN Whites 3527 (27.1%) 981 (32.2%) 1721 (29.9%) 825 (19.5%)
 Washington County, MD Whites 3373 (25.9%) 902 (29.6%) 1623 (28.2%) 848 (20%)
 Forsyth County, NC Whites 2974 (22.8%) 961 (31.6%) 1400 (24.3%) 613 (14.5%)
 Forsyth County, NC Blacks 344 (2.6%) 18 (0.6%) 94 (1.6%) 232 (5.5%)
 Jackson, MS Blacks 2821 (21.6%) 184 (6%) 921 (16%) 1716 (40.5%)
Education, n (%) a
 < High School 2785 (21.4%) 562 (18.5%) 1181 (20.5%) 1042 (24.6%)
 High School, GED, or Vocational School 5451 (41.8%) 1358 (44.6%) 2392 (41.5%) 1701 (40.2%)
 College, Graduate, or Professional School 4803 (36.8%) 1126 (37%) 2186 (38%) 1491 (35.2%)
BMI (kg/m2), mean (SD) 28.0 (5.4) 26.3 (4.2) 27.8 (5) 29.5 (6.3)
Physical activity index, mean (SD) a 2.4 (0.8) 2.7 (0.8) 2.5 (0.8) 2.2 (0.7)
Current Smoker, n (%) 2857 (21.9%) 595 (19.5%) 1149 (20.0%) 1113 (26.3%)
Current Drinker, n (%) 7349 (56.4%) 1920 (63.0%) 3365 (58.4%) 2064 (48.8%)
Systolic Blood Pressure (mmHg), mean (SD) 121.5 (18.9) 119.2 (18.0) 120.8 (18.4) 124.1 (19.8)
Use of Hypertension Medications, n (%) 4282 (32.8%) 836 (27.5%) 1828 (31.7%) 1618 (38.2%)
Total Cholesterol (mg/dL), mean (SD) 210.1 (39.5) 209.3 (38) 210.3 (38.6) 210.4 (41.6)
HDL Cholesterol (mg/dL), mean (SD) 49.7 (16.8) 51.2 (17.9) 48.7 (16.1) 50.1 (16.8)
Use of Cholesterol Medications, n (%) 830 (6.4%) 225 (7.4%) 382 (6.6%) 223 (5.3%)
Diabetes, n (%) 1913 (14.7%) 272 (8.9%) 789 (13.7%) 852 (20.1%)
Prevalent Coronary Heart Disease, n (%) 753 (5.8%) 192 (6.3%) 333 (5.8%) 228 (5.4%)
Prevalent stroke, n (%) 252 (1.9%) 38 (1.3%) 116 (2%) 98 (2.3%)
eGFR (mL/min/1.73 m2), mean (SD) 96.3 (15.8) 92.7 (14) 95.5 (14.7) 99.9 (17.6)
Parathyroid hormone (pg/mL), mean (SD) 42.6 (23.9) 36.8 (12.7) 41.3 (18.6) 48.7 (33.3)
Calcium (mg/dL), mean (SD) 9.4 (0.4) 9.3 (0.4) 9.4 (0.4) 9.4 (0.5)
Phosphate (mg/dL), mean (SD) 3.5 (0.5) 3.5 (0.5) 3.5 (0.5) 3.6 (0.5)
Thyroid stimulating hormone (mIU/L), median (IQI) 1.8 (1.2–2.7) 1.9 (1.3–2.8) 1.8 (1.2–2.7) 1.7 (1.1–2.6)
  1. Abbreviations: ARIC Atherosclerosis Risk in Communities; eGFR Estimated Glomerular Filtration Rate; IQI Interquartile interval
  2. a Measured at ARIC visit 1
  3. b To convert 25(OH) D from ng/mL to nmol/L, multiply by 2.496