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Table 1 Baseline Characteristics for INVEST-GENES Participants

From: Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population

Characteristic

Control group(n = 903)

IS group (n = 1078)

P value

 Age(years)

57.0 ± 14.9

64.4 ± 12.3

0.486

 Sex(male%)

474(52.5)

677(62.8)

<  10− 3

 Hypertension (%)

154(17.1)

729(67.6)

<  10− 3

 Diabetes (%)

59(6.5)

361(33.5)

<  10−3

 Hyperlipidemia (%)

90(10.0)

177(16.4)

<  10−3

 Coronary heart disease (%)

10(1.1)

115(10.7)

<  10−3

 Smoking (%)

244(27.0)

369 (34.2)

0.001

 Alcohol consumption(%)

175(19.6)

235(21.9)

0.214

 TG(mmol/L)

1.50 ± 1.13

2.27 ± 24.2

0.342

 TC(mmol/L)

4.36 ± 1.03

4.27 ± 2.73

0.311

 HDL-C(mmol/L)

1.36 ± 0.43

1.25 ± 0.50

<  10−3

 LDL-C(mmol/L)

2.73 ± 7.05

2.47 ± 0.96

0.230

 Fibrinogen levels (mmol/L)

2.20 ± 1.59

3.16 ± 1.00

<  10−3

 Plt(10^9/L)

178.5 ± 72.1

169.0 ± 66.70

0.021

Characteristic

LAA group (n = 405)

CES group(n = 136)

SVO group(n = 537)

P value

 Age(years)

63.2 ± 12.6

64.5 ± 12.9

64.9 ± 11.9

0.079

 Sex(male%)

274(67.7)

62(45.6)

341(63.5)

<  10−3

 Hypertension (%)

268(66.2)

65(47.8)

396(67.6)

<  10−3

 Diabetes (%)

132(32.6)

24(17.6)

205(38.2)

<  10−3

 Hyperlipidemia (%)

68(16.8)

13(9.6)

96(17.9)

0.063

 Coronary heart disease (%)

45(11.1)

18(13.2)

52(9.7)

0.457

 Smoking (%)

162(40.0)

25(18.4)

182(33.9)

<  10−3

 Alcohol consumption(%)

102 (25.2)

17(12.6)

116(21.7)

0.009

 TG(mmol/L)

1.65 ± 1.22

1.26 ± 0.66

2.52 ± 27.79

0.042

 TC(mmol/L)

4.51 ± 4.88

4.00 ± 1.58

4.21 ± 1.15

0.367

 HDL-C(mmol/L)

1.24 ± 0.68

1.30 ± 0.43

1.24 ± 0.40

0.926

 LDL-C(mmol/L)

2.44 ± 0.94

2.64 ± 3.87

2.49 ± 0.99

0.084

 Fibrinogen levels (mmol/L)

3.22 ± 0.97

2.98 ± 1.04

3.16 ± 1.00

0.012

 Plt(10^9/L)

171.2 ± 63.5

151.5 ± 61.0

171.0 ± 67.2

0.003

  1. count data:mean ± SD, measurement data:(%)
  2. P < 0.05 in bold