Table 2 Drugs that contraindicate initiation of fingolimod
Contraindicate initiation of fingolimod in all settings | Contraindicate initiation of fingolimod in patient’s home but not in a medical facility | |
|---|---|---|
Class Ia or class III antiarrhythmic drugs | Drugs that lower heart rate | Drugs that prolong QT interval with risk of torsades de pointes |
Amiodarone | Calcium-channel blockers: | Anagrelide |
Dofetilide | Diltiazem | Arsenic trioxide |
Disopyramide | Verapamil | Azithromycin |
Dronedarone | Cardioselective β-blockers: | Chloroquine |
Ibutilide | Acebutolol | Chlorpromazine |
Procainamide | Atenolol | Ciprofloxacin |
Quinidine | Betaxolol | Citalopram |
Sotalol | Bisoprolol | Cilostazol |
Esmolol | Clarithromycin | |
Metoprolol | Cocaine | |
Nebivolol | Donepezil | |
β-Blockers with intrinsic sympathomimetic activity: | Droperidol | |
Acebutolol | Erythromycin | |
Carteolol | Escitalopram | |
Penbutolol | Flecainide | |
Pindolol | Fluconazole | |
α-/β-Blockers: | Halofantrine | |
Carvedilol | Haloperidol | |
Labetalol | Levofloxacin | |
Nonselective β-blockers: | Methadone | |
Levobunolol | Moxifloxacin | |
Metipranolol | Ondansetron | |
Nadolol | Oxaliplatin | |
Propranolol | Papaverine hydrochloride | |
Sotalol | Pentamidine | |
Timolol | Pimozide | |
Other: | Propofol | |
Adenosine | Sevoflurane | |
Clonidine | Thioridazine | |
Digoxin | Vandetanib | |
Donepezil | ||
Ivabradine | ||