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Table 2 Clinical characteristics and CNS relapse types

From: Parenchymal central nervous system involvement in aggressive B-cell lymphoma: retrospective analysis of clinical and MRI features in a Chinese population

Characteristics Isolated CNS Synchronic CNS and systemic disease P value*
  N (%) N (%)  
Age
  ≤ 60 10 (47.6) 3 (60.0) 1.000
  > 60 11 (52.4) 2 (40.0)  
Relapse time
  ≤ 1 year 5 (23.8) 4 (80.0) 0.034
  > 1 year 16 (76.2) 1 (20.0)  
Primary site
 Lymph node 9 (42.9) 3 (60.0) 0.635
 Extra node 12 (57.1) 2 (40.0)  
Intravenous MTX
 Yes 2 (9.5) 0 (0.0) 1.000
 No 19 (90.5) 5 (100)  
Rituximab
 Yes 10 (47.6) 1 (20.0) 0.356
 No 11 (52.4) 4 (80.0)  
  1. Methotrexate, MTX; * Fisher’s Exact Test