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Table 2 Calendar-year analysis of classified medical costs PPPM for MS patients (values in 2016 were adjusted)

From: Recent transition of medical cost and relapse rate of multiple sclerosis in Japan based on analysis of a health insurance claims database

PPPM

2008

2009

2010

2011

2012

2013

2014

2015

2016

Total

¥87,640

¥88,839

¥90,931

¥80,813

¥77,539

¥87,358

¥96,332

¥100,937

¥102,846

Inpatient

 Total

¥43,581

¥48,008

¥43,561

¥37,393

¥34,983

¥31,847

¥29,508

¥30,235

¥30,993

 Medical procedure

¥31,606

¥35,608

¥35,326

¥30,854

¥27,042

¥24,896

¥22,092

¥22,920

¥24,037

 Imaging (CT, MRI)

¥1310

¥1107

¥918

¥916

¥829

¥804

¥739

¥663

¥661

 Labo test

¥3315

¥2726

¥1804

¥1704

¥2060

¥1723

¥1655

¥1612

¥1712

 Prescription drug (DMT)

¥901

¥597

¥529

¥937

¥987

¥1227

¥1089

¥1160

¥946

 Prescription drug (relapse treatment)

¥350

¥531

¥278

¥320

¥270

¥249

¥198

¥142

¥132

 Prescription drug (others)

¥6098

¥7437

¥4708

¥2662

¥3795

¥2948

¥3735

¥3739

¥3505

Outpatient

 Total

¥44,059

¥40,831

¥47,370

¥43,420

¥42,556

¥55,512

¥66,824

¥70,701

¥71,854

 Medical procedure

¥5756

¥5608

¥7434

¥6620

¥5718

¥4999

¥4668

¥4134

¥4322

 Imaging (CT, MRI)

¥1369

¥1423

¥1319

¥1232

¥1483

¥1944

¥1837

¥1695

¥1606

 Labo test

¥1754

¥2420

¥2116

¥2217

¥2252

¥2543

¥2608

¥2633

¥2591

 Prescription drug (DMT)

¥23,039

¥19,792

¥25,630

¥24,050

¥24,593

¥37,210

¥47,353

¥50,866

¥51,351

 Prescription drug (relapse treatment)

¥190

¥134

¥214

¥224

¥108

¥115

¥106

¥86

¥58

 Prescription drug (others)

¥11,951

¥11,454

¥10,657

¥9077

¥8402

¥8701

¥10,252

¥11,288

¥11,926

Trend of total medical cost (ratio to 2008)

1.00

1.01

1.04

0.92

0.88

1.00

1.10

1.15

1.17

Trend of inpatient cost (ratio to 2008)

1.00

1.10

1.00

0.86

0.80

0.73

0.68

0.69

0.71

Trend of outpatient DMT cost (ratio to 2008)

1.00

0.86

1.11

1.04

1.07

1.62

2.06

2.21

2.23