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Table 1 Baseline Characteristics of Patients with PMD and Non-PMD

From: The association between high-sensitivity C-reactive protein at admission and progressive motor deficits in patients with penetrating artery infarctions

VariablePMD (n = 85)Non-PMD (n = 459)P
Demographic characteristics
 Age, years67.8 ± 11.664.9 ± 11.80.038
 Male, %60 (70.6)327 (71.2)0.903
Vascular risk factors, %
 Hypertension56 (65.9)304 (66.2)0.950
 Diabetes mellitus44 (51.8)117 (25.5)< 0.001
 Dyslipidemia15 (17.6)76 (16.6)0.805
 Current smoking30 (35.3)191 (41.6)0.276
 Current drinking19 (22.4)143 (31.2)0.197
 Previous stroke7 (8.2)60 (13.1)0.213
 Peripheral artery disease4 (4.7)12 (2.6)0.294
 Coronary artery disease12 (14.1)54 (11.8)0.542
Clinical data
 Previous antiplatelet, %10 (11.8)47 (10.2)0.673
 Previous statin, %2 (2.4)14 (3.1)0.727
 SBP, mmHg142.8 ± 19.8144.9 ± 20.80.445
 DBP, mmHg84.7 ± 11.786.0 ± 12.40.449
 Body mass index, kg/m224.3 ± 4.324.5 ± 3.30.773
 Initial total NIHSS, score3 (1–4)2 (2–4)0.728
 White matter lesions, %60 (70.6)294 (64.1)0.246
 Intravenous thrombolysis, %15 (17.6)76 (16.6)0.805
 Infra-tentorial infarction, %42 (49.4)244 (53.2)0.525
 Supra-tentorial infarction, %43 (50.6)215 (46.8)0.525
 MCA stenosis, %
  046 (54.1)261 (56.9)0.639
   ≤ 50%35 (41.2)173 (37.7)0.544
  >50%4 (4.7)25 (5.4)0.780
 VBA stenosis, %
  040 (47.1)258 (56.2)0.577
   ≤ 50%31 (36.5)172 (37.5)0.861
  >50%9 (10.6)30 (6.5)0.183
 Carotid artery atheromatosis, %
  Absence39 (45.9)183 (39.9)0.300
  Moderate39 (45.9)239 (52.7)0.295
  Significant7 (8.2)37 (8.1)0.957
 Silent lacunar infarcts, %42 (49.4)204 (44.4)0.398
 OMT, day1 (1,2)1 (1,2)0.589
 Antibiotic use, %23 (27.1)92 (20.0)0.146
Laboratory data
 Leukocyte number, 10^98.5 ± 2.48.0 ± 4.30.348
 TC, mmol/L4.4 ± 1.24.5 ± 1.00.338
 TG, mmol/L2.0 ± 1.41.7 ± 1.10.073
 HDL, mmol/L1.0 ± 0.21.1 ± 0.40.306
 LDL, mmol/L2.7 ± 0.82.7 ± 0.80.902
 FBG, mmol/L7.5 ± 3.55.7 ± 2.1< 0.001
 Glycated hemoglobin, %7.5 ± 2.46.2 ± 1.30.002
 Homocysteine, umol/L15.6 ± 8.016.1 ± 8.30.519
 Hs-CRP, mg/L5.9 (4.0–9.8)2.0 (1.3–3.8)< 0.001
  1. Abbreviations: SBP, Systolic blood pressure; DBP, Diastolic blood pressure; National Institutes of Health Stroke Scale; MCA, Middle cerebral artery; VBA, Vertebro-basilar artery; OMT, Onset to the measurement of hs-CRP time; TC, Total cholesterol; TG, Triglyceride; HDL, High density lipoprotein; LDL, Low density lipoprotein; FBG, Fast blood glucose
  2. ‘Antibiotic use’ means ‘the antibiotic use during hospitalisation’