Table 1 Baseline Characteristics of Patients with PMD and Non-PMD
Variable | PMD (n = 85) | Non-PMD (n = 459) | P |
|---|---|---|---|
Demographic characteristics | |||
Age, years | 67.8 ± 11.6 | 64.9 ± 11.8 | 0.038 |
Male, % | 60 (70.6) | 327 (71.2) | 0.903 |
Vascular risk factors, % | |||
Hypertension | 56 (65.9) | 304 (66.2) | 0.950 |
Diabetes mellitus | 44 (51.8) | 117 (25.5) | < 0.001 |
Dyslipidemia | 15 (17.6) | 76 (16.6) | 0.805 |
Current smoking | 30 (35.3) | 191 (41.6) | 0.276 |
Current drinking | 19 (22.4) | 143 (31.2) | 0.197 |
Previous stroke | 7 (8.2) | 60 (13.1) | 0.213 |
Peripheral artery disease | 4 (4.7) | 12 (2.6) | 0.294 |
Coronary artery disease | 12 (14.1) | 54 (11.8) | 0.542 |
Clinical data | |||
Previous antiplatelet, % | 10 (11.8) | 47 (10.2) | 0.673 |
Previous statin, % | 2 (2.4) | 14 (3.1) | 0.727 |
SBP, mmHg | 142.8 ± 19.8 | 144.9 ± 20.8 | 0.445 |
DBP, mmHg | 84.7 ± 11.7 | 86.0 ± 12.4 | 0.449 |
Body mass index, kg/m2 | 24.3 ± 4.3 | 24.5 ± 3.3 | 0.773 |
Initial total NIHSS, score | 3 (1–4) | 2 (2–4) | 0.728 |
White matter lesions, % | 60 (70.6) | 294 (64.1) | 0.246 |
Intravenous thrombolysis, % | 15 (17.6) | 76 (16.6) | 0.805 |
Infra-tentorial infarction, % | 42 (49.4) | 244 (53.2) | 0.525 |
Supra-tentorial infarction, % | 43 (50.6) | 215 (46.8) | 0.525 |
MCA stenosis, % | |||
0 | 46 (54.1) | 261 (56.9) | 0.639 |
≤ 50% | 35 (41.2) | 173 (37.7) | 0.544 |
>50% | 4 (4.7) | 25 (5.4) | 0.780 |
VBA stenosis, % | |||
0 | 40 (47.1) | 258 (56.2) | 0.577 |
≤ 50% | 31 (36.5) | 172 (37.5) | 0.861 |
>50% | 9 (10.6) | 30 (6.5) | 0.183 |
Carotid artery atheromatosis, % | |||
Absence | 39 (45.9) | 183 (39.9) | 0.300 |
Moderate | 39 (45.9) | 239 (52.7) | 0.295 |
Significant | 7 (8.2) | 37 (8.1) | 0.957 |
Silent lacunar infarcts, % | 42 (49.4) | 204 (44.4) | 0.398 |
OMT, day | 1 (1,2) | 1 (1,2) | 0.589 |
Antibiotic use, % | 23 (27.1) | 92 (20.0) | 0.146 |
Laboratory data | |||
Leukocyte number, 10^9 | 8.5 ± 2.4 | 8.0 ± 4.3 | 0.348 |
TC, mmol/L | 4.4 ± 1.2 | 4.5 ± 1.0 | 0.338 |
TG, mmol/L | 2.0 ± 1.4 | 1.7 ± 1.1 | 0.073 |
HDL, mmol/L | 1.0 ± 0.2 | 1.1 ± 0.4 | 0.306 |
LDL, mmol/L | 2.7 ± 0.8 | 2.7 ± 0.8 | 0.902 |
FBG, mmol/L | 7.5 ± 3.5 | 5.7 ± 2.1 | < 0.001 |
Glycated hemoglobin, % | 7.5 ± 2.4 | 6.2 ± 1.3 | 0.002 |
Homocysteine, umol/L | 15.6 ± 8.0 | 16.1 ± 8.3 | 0.519 |
Hs-CRP, mg/L | 5.9 (4.0–9.8) | 2.0 (1.3–3.8) | < 0.001 |