Table 3 Logistic regression analysis for risk factors with PMD

 Age, years

1.021 (1.001–1.042)

1.025 (1.001–1.048)

 Male

0.969 (0.583–1.611)

 Hypertension

0.985 (0.604–1.604)

 Diabetes mellitus

3.137 (1.952–5.041)

1.757 (0.934–3.304)

 Dyslipidemia

1.080 (0.587–1.987)

 Current smoking

0.765 (0.473–1.239)

 Current drinking

0.707 (0.420–1.191)

 Previous stroke

0.597 (0.263–1.354)

 Previous antiplatelet

1.169 (0.566–2.415)

 Previous statin

0.766 (0.171–3.433)

 SBP

0.995 (0.983–1.006)

 DBP

0.992 (0.973–1.011)

 Body mass index

0.985 (0.913–1.063)

 Initial total NIHSS

1.018 (0.941–1.103)

 White matter lesions

1.347 (0.814–2.230)

 Intravenous thrombolysis

1.080 (0.587–1.987)

 Infra-tentorial infarction

1.162 (0.731–1.846)

 Silent lacunar infarcts

1.221 (0.768–1.941)

 0

1.118 (0.702–1.779)

  ≤ 50%

1.157 (0.722–1.854)

 >50%

0.926 (0.539–1.590)

 0

1.141 (0.717–1.815)

  ≤ 50%

0.958 (0.593–1.549)

 >50%

1.301 (0.879–1.926)

 Antibiotic use

1.480 (0.871–2.515)

 Quartile 1

Reference

Reference

 Quartile 2

0.416 (0.105–1.642)

0.468 (0.110–1.981)

 Quartile 3

5.216 (2.203–12.349)

5.191(1.974–13.649)

 Quartile 4

9.113 (3.933–21.116)

9.786 (3.819–25.075)

 Leukocyte number, 10^{^9}

0.957 (0.879–1.043)

 TC, mmol/L

0.930 (0.743–1.164)

 TG, mmol/L

1.169 (0.983–1.391)

 HDL, mmol/

0.548 (0.220–1.365)

 LDL, mmol/L

0.876 (0.657–1.169)

 FBG, mmol/L

1.254 (1.152–1.364)

1.067 (0.934–1.218)

 Glycated hemoglobin, %

1.495 (1.313–1.701)

1.351 (1.095–1.668)

 Homocysteine, umol/L

0.992 (0.960–1.026)