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Table 3 Logistic regression analysis for risk factors with PMD

From: The association between high-sensitivity C-reactive protein at admission and progressive motor deficits in patients with penetrating artery infarctions

VariableUnadjusted OR (95%CI)PAdjusted OR (95%CI)P
Demographic characteristics
 Age, years1.021 (1.001–1.042)0.0381.025 (1.001–1.048)0.048
 Male0.969 (0.583–1.611)0.903  
Vascular risk factors
 Hypertension0.985 (0.604–1.604)0.950  
 Diabetes mellitus3.137 (1.952–5.041)0.0011.757 (0.934–3.304)0.080
 Dyslipidemia1.080 (0.587–1.987)0.805  
 Current smoking0.765 (0.473–1.239)0.227  
 Current drinking0.707 (0.420–1.191)0.192  
 Previous stroke0.597 (0.263–1.354)0.217  
Clinical data
 Previous antiplatelet1.169 (0.566–2.415)0.674  
 Previous statin0.766 (0.171–3.433)0.728  
 SBP0.995 (0.983–1.006)0.374  
 DBP0.992 (0.973–1.011)0.398  
 Body mass index0.985 (0.913–1.063)0.694  
 Initial total NIHSS1.018 (0.941–1.103)0.653  
 White matter lesions1.347 (0.814–2.230)0.247  
 Intravenous thrombolysis1.080 (0.587–1.987)0.805  
 Infra-tentorial infarction1.162 (0.731–1.846)0.525  
 Silent lacunar infarcts1.221 (0.768–1.941)0.398  
MCA stenosis
 01.118 (0.702–1.779)0.639  
  ≤ 50%1.157 (0.722–1.854)0.544  
 >50%0.926 (0.539–1.590)0.780  
VBA stenosis
 01.141 (0.717–1.815)0.578  
  ≤ 50%0.958 (0.593–1.549)0.861  
 >50%1.301 (0.879–1.926)0.188  
 Antibiotic use1.480 (0.871–2.515)0.147  
Hs-CRP distribution
 Quartile 1Reference Reference 
 Quartile 20.416 (0.105–1.642)0.2110.468 (0.110–1.981)0.302
 Quartile 35.216 (2.203–12.349)0.0015.191(1.974–13.649)0.002
 Quartile 49.113 (3.933–21.116)0.0019.786 (3.819–25.075)0.001
Laboratory data
 Leukocyte number, 10^90.957 (0.879–1.043)0.320  
 TC, mmol/L0.930 (0.743–1.164)0.528  
 TG, mmol/L1.169 (0.983–1.391)0.077  
 HDL, mmol/0.548 (0.220–1.365)0.196  
 LDL, mmol/L0.876 (0.657–1.169)0.370  
 FBG, mmol/L1.254 (1.152–1.364)0.0011.067 (0.934–1.218)0.340
 Glycated hemoglobin, %1.495 (1.313–1.701)0.0011.351 (1.095–1.668)0.005
 Homocysteine, umol/L0.992 (0.960–1.026)0.646  
  1. Abbreviations: SBP, Systolic blood pressure; DBP, Diastolic blood pressure; National Institutes of Health Stroke Scale; MCA, Middle cerebral artery; VBA, Vertebro-basilar artery;TC, Total cholesterol; TG, Triglyceride; HDL, High density lipoprotein; LDL, Low density lipoprotein; FBG, Fast blood glucose