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Table 2 Quality evaluation of the included studies according to the QUADAS-2 [18]

From: Detecting delirium in patients with acute stroke: a systematic review of test accuracy

Study, author, year [reference]

Risk of Bias

Applicability Concerns

 

Patient Selection

Index Test

Reference Standard

Flow and Timing

Patient Selection

Index Test

Reference Standard

 

Was a consecutive or random sample of patients enrolled?

Was a case-control design avoided?

Did the study avoid inappropriate exclusions?

Were the index test results interpreted without knowledge of the results of the reference standard?

If a threshold was used, was it pre-specified?

Is the reference standard likely to correctly classify the target condition?

Were the reference standard results interpreted without knowledge of the results in the index test?

Was there an appropriate interval between the index test and reference standard?

Did all patients receive the same reference standard?

Were all patients included in the analysis?

Are there concerns that the included patients and setting do not match the review question?

Are there concerns that the index test, its conduct, or its interpretation differ from the review question?

Are there concerns that the target condition as defined by the reference standard does not match the question?

Infante et al., 2017 [20]

Y

Y

N

N

Y

Y

N

Y

Y

Y

N

N

N

Kutlubaev et al., 2016 [21]

Y

Y

Y

?

Y

Y

?

Y

Y

Y

N

N

N

Lees et al., 2013

[22]

Y

Y

N

Y

Y

?

Y

Y

Y

Y

N

N

N

Mitasova et al., 2012 [8]

Y

Y

N

Y

Y

Y

Y

?

Y

Y

Y

N

N

  1. Y: yes, N: no,?: unclear (not enough data documented in the study), QUADAS-2: Quality Assessment of Diagnostic Accuracy Studies-2.