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Fig. 2 | BMC Neurology

Fig. 2

From: Different imaging patterns of PCNSL and IVL: a case report

Fig. 2

The outcome of brain biopsy. a Hematoxylin and eosin (H&E) stained slide (× 200) shows a diffuse large B-cell lymphoma. The neoplastic cells have a uniform cytological appearance with medium-sized to large lymphoid cells with usually oval to round vesicular nuclei containing fine chromatin. The cytoplasm is usually scant and amphophilic. b Hematoxylin and eosin (H&E) stained slide (× 400) shows large malignant tumor cells with prominent single central nucleoli (star). Malignant cells were not observed in the intravascular space (arrow). (C) CD20 immunostaining (× 400). It shows strong membranous and perinuclear labeling of the malignant cells for CD20

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