Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Fig. 1 | BMC Neurology

Fig. 1

From: Evaluating the cerebrospinal fluid ctDNA detection by next-generation sequencing in the diagnosis of meningeal Carcinomatosis

Fig. 1

Head contrast enhanced MRI (a and b) of one patient showed abnormally uniform leptomeningeal enhancement. At the same time, no neoplastic cells were found in CSF by CSF cytology (c) while CSF sample revealed ctDNA and showed cancer-associated gene mutations of PTEN K13Q (0.464%), TP53 P301Q (0.809%), VHL R161Q (0.213%), CDKN2A A68T(0.235%) and FGFR2 Y375C (0.207%) by NGS. CSF cytology (d) 1 year later showed a large number of neoplastic cells

Back to article page