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Fig. 2 | BMC Neurology

Fig. 2

From: Late-onset riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency (MADD): case reports and epidemiology of ETFDH gene mutations

Fig. 2

Genetic epidemiology of the c.250G > A ETFDH mutation. Geographic distribution of the Southern Min population (highlighted in red); reported number of MADD case with confirmed ETFDH mutation; and the allele frequency of the c.250G > A ETFDH mutation among all reported ETFDH mutations in different regions of China and neighboring countries. The Southern Min people is believed to have migrated from middle China around Henan Province (origin) to the Southern Min region (first migration) over a thousand years ago, and further travelled to Southeast Asia and overseas in a second migration in the past centuries. Map downloaded and modified from Glottolog 4.1 edited by HMS, H&F, R& HPM, M/ CC BY https://glottolog.org/resource/languoid/id/minn1248.bigmap.html#3/23.63/115.88

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