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Fig. 2 | BMC Neurology

Fig. 2

From: Multimodal MRI of grey matter, white matter, and functional connectivity in cognitively healthy mutation carriers at risk for frontotemporal dementia and Alzheimer's disease

Fig. 2

White matter FA analysis. Differences in FA (or lack thereof) are shown for each contrast (e.g., MAPT/GRN mutation carriers greater or smaller than controls; APOE4 carriers greater or smaller than controls; MAPT/GRN carrier-control differences greater or smaller than APOE4 carrier-control differences). Mean skeleton maps are shown in green; skeletonised significant results were thickened for better visualisation. Four clusters of FA reductions were found in APOE4 carriers compared to controls (middle left panel). Colour bar represents significance. APOE4, apolipoprotein E ε4; FA, fractional anisotropy; MAPT/GRN, microtubule-associated protein tau / progranulin

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