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Table 5 Severity and frequency of impacts on daily life due to side effects of myasthenia gravis treatment (N = 124)

From: Understanding side effects of therapy for myasthenia gravis and their impact on daily life

Impact StatementSeverity1Frequency2
nMean (SD)nMean (SD)
1. To become depressed1212.1 (1.0)1232.0 (0.9)
2. Affected my ability to work or attend school1182.3 (1.1)1222.2 (1.1)
3. Made me moody1222.1 (1.0)1232.1 (0.9)
4. Caused me to sleep more than usual1211.8 (0.9)1201.8 (1.0)
5. Caused me to discontinue or avoid taking my medications1191.8 (1.1)1231.8 (1.0)
6. Caused insomnia or interferes with my sleep. I am not able to get a good night’s sleep1222.4 (1.1)1242.4 (1.1)
7. Caused me to require additional medical procedures1221.7 (1.1)1241.5 (0.9)
8. Interfered with my ability to care for my family1202.0 (1.0)1222.0 (1.1)
9. Made me very frustrated and/or demoralized1212.1 (1.0)1222.1 (1.0)
10. Caused me to visit the emergency room and/or be hospitalized1191.9 (1.2)1221.5 (0.8)
11. Sometimes made my MG symptoms worse1212.0 (1.0)1211.7 (0.8)
12. Have limited my daily activities1202.3 (1.0)1232.2 (1.1)
13. Have limited me physically1212.5 (1.1)1232.5 (1.1)
14. Made me very irritable and short-tempered1221.9 (1.0)1231.9 (1.0)
15. With the MG treatment that I’m prescribed it is difficult to adjust the correct dose that I need to control my MG symptoms1221.7 (0.9)1231.7 (0.9)
16. Have made me feel very self-conscious, ugly, and/or unattractive1221.9 (1.1)1232.0 (1.1)
17. Made me uncomfortable being around other people1202.0 (1.0)1191.9 (1.0)
18. Made me worry about catching infections from other people so I reduced my social activities1192.4 (1.0)1222.4 (1.1)
19. Have limited my mobility1212.2 (1.1)1232.2 (1.1)
20. Have caused me to be so tired, I avoid leaving the house or going out in public1202.0 (1.0)1222.0 (1.0)
21. Decreased my quality of life1192.3 (1.1)1232.3 (1.1)
22. Side effects sometimes caused me to have to choose between tolerating my MG symptoms or the side effects of medication1222.0 (1.1)1222.0 (1.1)
23. Made life very stressful and/or overwhelming1191.9 (1.0)1232.0 (1.1)
  1. 1Severity was assessed on a 1–4 scale, with 1 being “no impact” and 4 being “severe impact”
  2. 2Frequency was assessed on a 1–4 scale, with 1 being “never” and 4 being “almost always”