Table 5 Severity and frequency of impacts on daily life due to side effects of myasthenia gravis treatment (N = 124)
From: Understanding side effects of therapy for myasthenia gravis and their impact on daily life
Impact Statement | Severity1 | Frequency2 | ||
|---|---|---|---|---|
n | Mean (SD) | n | Mean (SD) | |
1. To become depressed | 121 | 2.1 (1.0) | 123 | 2.0 (0.9) |
2. Affected my ability to work or attend school | 118 | 2.3 (1.1) | 122 | 2.2 (1.1) |
3. Made me moody | 122 | 2.1 (1.0) | 123 | 2.1 (0.9) |
4. Caused me to sleep more than usual | 121 | 1.8 (0.9) | 120 | 1.8 (1.0) |
5. Caused me to discontinue or avoid taking my medications | 119 | 1.8 (1.1) | 123 | 1.8 (1.0) |
6. Caused insomnia or interferes with my sleep. I am not able to get a good night’s sleep | 122 | 2.4 (1.1) | 124 | 2.4 (1.1) |
7. Caused me to require additional medical procedures | 122 | 1.7 (1.1) | 124 | 1.5 (0.9) |
8. Interfered with my ability to care for my family | 120 | 2.0 (1.0) | 122 | 2.0 (1.1) |
9. Made me very frustrated and/or demoralized | 121 | 2.1 (1.0) | 122 | 2.1 (1.0) |
10. Caused me to visit the emergency room and/or be hospitalized | 119 | 1.9 (1.2) | 122 | 1.5 (0.8) |
11. Sometimes made my MG symptoms worse | 121 | 2.0 (1.0) | 121 | 1.7 (0.8) |
12. Have limited my daily activities | 120 | 2.3 (1.0) | 123 | 2.2 (1.1) |
13. Have limited me physically | 121 | 2.5 (1.1) | 123 | 2.5 (1.1) |
14. Made me very irritable and short-tempered | 122 | 1.9 (1.0) | 123 | 1.9 (1.0) |
15. With the MG treatment that I’m prescribed it is difficult to adjust the correct dose that I need to control my MG symptoms | 122 | 1.7 (0.9) | 123 | 1.7 (0.9) |
16. Have made me feel very self-conscious, ugly, and/or unattractive | 122 | 1.9 (1.1) | 123 | 2.0 (1.1) |
17. Made me uncomfortable being around other people | 120 | 2.0 (1.0) | 119 | 1.9 (1.0) |
18. Made me worry about catching infections from other people so I reduced my social activities | 119 | 2.4 (1.0) | 122 | 2.4 (1.1) |
19. Have limited my mobility | 121 | 2.2 (1.1) | 123 | 2.2 (1.1) |
20. Have caused me to be so tired, I avoid leaving the house or going out in public | 120 | 2.0 (1.0) | 122 | 2.0 (1.0) |
21. Decreased my quality of life | 119 | 2.3 (1.1) | 123 | 2.3 (1.1) |
22. Side effects sometimes caused me to have to choose between tolerating my MG symptoms or the side effects of medication | 122 | 2.0 (1.1) | 122 | 2.0 (1.1) |
23. Made life very stressful and/or overwhelming | 119 | 1.9 (1.0) | 123 | 2.0 (1.1) |