Skip to main content

Table 2 The association between symptoms and genetic models (additive and dominant models) of NMD3 rs34016896

From: Association between NMD3 and symptoms of Parkinson’s disease in Chinese patients

 

Additive model

Dominant model

Dominant model (adjusted)*

p value

OR

95% CI

p value

OR

95% CI

Hallucination

0.025

0.368

1.78

(0.58, 7.79)

0.341

1.86

(0.59, 8.26)

Apathy

0.092

0.941

0.97

(0.49, 1.97)

0.955

0.98

(0.48, 2.01)

Excessive daytime sleepiness

0.444

0.908

0.95

(0.38, 2.15)

0.896

0.94

(0.38, 2.15)

Pain

0.696

0.474

0.77

(0.37, 1.56)

0.513

0.78

(0.37, 1.60)

Frequent urination

0.639

0.491

1.28

(0.64, 2.58)

0.526

1.27

(0.60, 2.72)

Constipation

0.930

0.656

0.85

(0.42, 1.71)

0.528

0.78

(0.36, 1.66)

Postural hypotension

0.007

0.052

2.38

(1.05, 6.16)

0.050

2.43

(1.05, 6.38)

Sialorrhea

0.487

0.600

1.20

(0.60, 2.42)

0.617

1.22

(0.56, 2.62)

RLS

0.905

0.266

0.66

(0.32, 1.40)

0.259

0.65

(0.31, 1.40)

Delusion

0.038

0.557

1.58

(0.42, 10.33)

0.605

1.51

(0.38, 10.10)

Double vision

0.197

0.144

3.02

(0.85, 19.31)

0.133

3.22

(0.86, 21.14)

Decreased attention

0.124

0.570

1.27

(0.58, 3.00)

0.554

1.29

(0.57, 3.14)

Decreased recent memory

0.064

0.227

1.54

(0.76, 3.09)

0.232

1.54

(0.76, 3.13)

Nocturia

0.870

0.845

1.08

(0.47, 2.34)

0.932

1.04

(0.43, 2.36)

Sexual dysfunction

0.188

0.272

1.64

(0.71, 4.27)

0.254

1.69

(0.72, 4.48)

Hypogeusia

0.202

0.827

1.08

(0.54, 2.22)

0.859

1.07

(0.53, 2.19)

Change of weight

0.073

0.323

0.49

(0.13, 2.38)

0.298

0.47

(0.12, 2.29)

Daytime sweatiness

0.449

0.964

1.02

(0.49, 2.17)

0.918

1.04

(0.49, 2.29)

Nocturnal sweatiness

0.405

0.847

0.93

(0.46, 1.96)

0.874

0.94

(0.45, 2.04)

Urgent urination or urinary incontinence

0.724

0.891

1.05

(0.52, 2.10)

0.946

1.03

(0.48, 2.18)

Sensitive to light

0.142

0.387

2.50

(0.47, 46.44)

0.381

2.55

(0.46, 47.88)

Sensitive to cold

0.484

0.589

1.30

(0.53, 3.66)

0.588

1.30

(0.53, 3.68)

Sensitive to hot

0.481

0.311

0.63

(0.27, 1.62)

0.283

0.60

(0.25, 1.59)

Anxiety

0.155

0.404

1.49

(0.62, 4.19)

0.335

1.64

(0.63, 4.86)

Depression

0.935

0.644

1.35

(0.43, 5.98)

0.664

1.34

(0.41, 6.09)

RBD

0.957

0.542

0.80

(0.39, 1.67)

0.498

0.77

(0.37, 1.65)

Olfactory dysfunction

0.784

0.845

1.08

(0.47, 2.34)

0.934

1.03

(0.44, 2.26)

  1. CI, confidence interval; OR, odds ratio; RBD, rapid eye movement sleep behavior disorder; RLS, restless legs syndrome
  2. *adjusted by age, gender and Hoehn-Yahr staging