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Table 2 The association between symptoms and genetic models (additive and dominant models) of NMD3 rs34016896

From: Association between NMD3 and symptoms of Parkinson’s disease in Chinese patients

 Additive modelDominant modelDominant model (adjusted)*
p valueOR95% CIp valueOR95% CI
Hallucination0.0250.3681.78(0.58, 7.79)0.3411.86(0.59, 8.26)
Apathy0.0920.9410.97(0.49, 1.97)0.9550.98(0.48, 2.01)
Excessive daytime sleepiness0.4440.9080.95(0.38, 2.15)0.8960.94(0.38, 2.15)
Pain0.6960.4740.77(0.37, 1.56)0.5130.78(0.37, 1.60)
Frequent urination0.6390.4911.28(0.64, 2.58)0.5261.27(0.60, 2.72)
Constipation0.9300.6560.85(0.42, 1.71)0.5280.78(0.36, 1.66)
Postural hypotension0.0070.0522.38(1.05, 6.16)0.0502.43(1.05, 6.38)
Sialorrhea0.4870.6001.20(0.60, 2.42)0.6171.22(0.56, 2.62)
RLS0.9050.2660.66(0.32, 1.40)0.2590.65(0.31, 1.40)
Delusion0.0380.5571.58(0.42, 10.33)0.6051.51(0.38, 10.10)
Double vision0.1970.1443.02(0.85, 19.31)0.1333.22(0.86, 21.14)
Decreased attention0.1240.5701.27(0.58, 3.00)0.5541.29(0.57, 3.14)
Decreased recent memory0.0640.2271.54(0.76, 3.09)0.2321.54(0.76, 3.13)
Nocturia0.8700.8451.08(0.47, 2.34)0.9321.04(0.43, 2.36)
Sexual dysfunction0.1880.2721.64(0.71, 4.27)0.2541.69(0.72, 4.48)
Hypogeusia0.2020.8271.08(0.54, 2.22)0.8591.07(0.53, 2.19)
Change of weight0.0730.3230.49(0.13, 2.38)0.2980.47(0.12, 2.29)
Daytime sweatiness0.4490.9641.02(0.49, 2.17)0.9181.04(0.49, 2.29)
Nocturnal sweatiness0.4050.8470.93(0.46, 1.96)0.8740.94(0.45, 2.04)
Urgent urination or urinary incontinence0.7240.8911.05(0.52, 2.10)0.9461.03(0.48, 2.18)
Sensitive to light0.1420.3872.50(0.47, 46.44)0.3812.55(0.46, 47.88)
Sensitive to cold0.4840.5891.30(0.53, 3.66)0.5881.30(0.53, 3.68)
Sensitive to hot0.4810.3110.63(0.27, 1.62)0.2830.60(0.25, 1.59)
Anxiety0.1550.4041.49(0.62, 4.19)0.3351.64(0.63, 4.86)
Depression0.9350.6441.35(0.43, 5.98)0.6641.34(0.41, 6.09)
RBD0.9570.5420.80(0.39, 1.67)0.4980.77(0.37, 1.65)
Olfactory dysfunction0.7840.8451.08(0.47, 2.34)0.9341.03(0.44, 2.26)
  1. CI, confidence interval; OR, odds ratio; RBD, rapid eye movement sleep behavior disorder; RLS, restless legs syndrome
  2. *adjusted by age, gender and Hoehn-Yahr staging