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Table 1 Subjects’ characteristic

From: A new approach to characterize postural deficits in chemotherapy-induced peripheral neuropathy and to analyze postural adaptions after an exercise intervention

 

Electrophysiology

Reflexes

Vibration sense

 

Patient

Sex

Height (cm)

Weight (kg)

Age (years)

Diagnosis

Status

Months since initial diagnosis (n)

Cycles of neurotoxic drugs (n)

NCV N.tibialis (m/s)

APA N.suralis (μV)

Achilles tendon

Patellar tendon

right

left

NtxS (score)

1

m

182

125

55–59

B-NHL

Partial remission

185

14

32

1.7

6/8

6/8

34

2

m

182

80

65–69

Multiple myeloma

Stable disease

58

34

0

0

+

5.5/8

0.5/8

29

3

f

161

86

60–64

Multiple myeloma

Relapse

82

7

28

6.05

4/8

3.5/8

24

4

f

162

60

65–69

Breast cancer

Stable disease

66

19

49

3.55

+

5/8

5/8

23

5

m

180

80

60–64

Multiple myeloma

Stable disease

8

4

39

1.55

(−)

(−)

0.5/8

1.5/8

34

6

m

167

92

60–64

Breast cancer

Stable disease

195

25

40

0

0.5/8

4/8

14

7

m

176

64

65–69

Rectal cancer

Progressive disease

118

79

37

0

0/8

0/8

23

8

m

188

107

40–44

Germ cell cancer

Complete remission

66

4

42

1

4/8

0/8

22

mean ± SD

m:f

6:2

174.8 ± 10.1

86.8 ± 21.5

60.8 ± 8.7

  

97.3 ± 64.8

23.3 ± 24.9

34.4 ± 14.9

1.7 ± 2.1

  

3.2 ± 2.5

2.6 ± 2.4

25.4 ± 6.3

Healthy control subjects

mean ± SD

m:f

9:6

17.0 ± 9.1

78.0 ± 6.3

59.6 ± 10.0

           
  1. APA action potential amplitude (normal values: ≥6 μV), B-NHL B-Non Hodgkin Lymphoma, f female, m male, NCV nerve conduction velocity (normal values: ≥41 m/s), NtxS neurotoxicity subscale of FACT/GOG (Functional Assessment of Cancer Therapy/Gynaecology Oncology Group) scored from 0 (severe symptoms) – 44 (no symptoms); SD, standard deviation; “-”, no reflex; “(−)”, reduced reflex; “+”, normal reflex