Fig. 3

Permeability imaging from six different patients is shown. Each panel has two thumbnail images and a larger permeability map. In each case, the upper thumbnail image is the time-to-peak (TTP) map and the lower thumbnail is the TTP map with the region of ischemia (relative TTP > 4 s) shaded in light blue. To the right of the thumbnails is the blood-brain permeability heat map within the regions of ischemia, color coded according to the color key at the bottom of the figure. The mean permeability derangement (MPD) is indicated in each panel for each patient. The three panels in the blue box on the left have MPD < 20%, whereas those in the purple box on the right have MPD > 20%. Panels a and b contrast two patients with large perfusion deficits, one below the threshold and one above. Similarly, panels c and d contrast two patients with more distal vessel occlusions. Panels E and F show two patients with an MPD very close to the threshold