Skip to main content

Table 1 Continuous variables are shown as mean ± SD, NIHSS and Age are shown as median and IQR, and categorical variables are shown as total (percent). DWI indicated diffusion-weighted imaging; NIHSS, National Institute of Health Stroke Scale; PWI, Perfusion-weighted Imaging; tPA, tissue-type plasminogen activator

From: Blood-brain barrier integrity of stroke patients presenting in an extended time window

 All Patients (N = 222)< 20% Permeability (N = 129)> 20% Permeability (N = 93)Univariate AnalysisMultivariate Analysis
Mean Permeability Derangement (%)27.9712.4549.45 
Age (median)73 (59–85)69 (58–83)76(64–86)p = 0.031p = 0.019
Sex (%)54.551.957.4p = 0.238 
NIHSS (median)6 (0–14)6 (3–13)6(2–14)p = 0.695 
PWI Volume (mL)18.5 (4.3–69.56)26.43 (8.9–83.72)10.42 (2.7–41.55)p = 0.012p = 0.007
DWI Volume (mL)2.95 (0.5–9.13)5.1 (0.82–11.19)1.132 (0.3383–6.86)p = 0.24 
Last Seen Normal to MRI (minutes)677 ± 303.5681 ± 300.32670 ± 309.50p = 0.781 
Found with Symptoms to MRI (minutes)364 ± 302.65389 ± 330.05327 ± 356.10p = 0.138 
Approximate Onset to MRI (minutes)511 ± 275.6531 ± 287.50482 ±257p = 0.195